Quadruple valve replacement for patients with carcinoid heart disease.

We report two cases of patients with carcinoid heart disease affecting all four valves. All four of the valves showed signs of regurgitation and were replaced using biological valves. Left-sided involvement is uncommon (5-10%), but can occur in the absence of an intracardiac shunt. Quadruple valve replacement in symptomatic patients can result in functional improvement with acceptable risks. © Indian Association of Cardiovascular-Thoracic Surgeons 2021.