Literature DB >> 34219858

Stress in the onset and aggravation of learning disabilities.

Olga V Burenkova1,2, Oksana Yu Naumova1,2,3, Elena L Grigorenko1,2,4.   

Abstract

Despite substantial grounds for such research, the role of chronic exposure to stressors in the onset and aggravation of learning disabilities (LDs) is largely unexplored. In this review, we first consider the hormonal, (epi)genetic, and neurobiological mechanisms that might underlie the impact of adverse childhood experiences, a form of chronic stressors, on the onset of LDs. We then found that stress factors combined with feelings of inferiority, low self-esteem, and peer victimization could potentially further aggravate academic failures in children with LDs. Since effective evidence-based interventions for reducing chronic stress in children with LDs could improve their academic performance, consideration of the role of exposure to stressors in children with LDs has both theoretical and practical importance, especially when delivered in combination with academic interventions.

Entities:  

Keywords:  HPA axis; adverse childhood experiences; children; cortisol; gene-environment interaction; learning disabilities

Year:  2021        PMID: 34219858      PMCID: PMC8244356          DOI: 10.1016/j.dr.2021.100968

Source DB:  PubMed          Journal:  Dev Rev        ISSN: 0273-2297


  88 in total

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Journal:  Endocr Rev       Date:  2000-02       Impact factor: 19.871

2.  Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement.

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Journal:  Neuroscience       Date:  2000       Impact factor: 3.590

3.  The impact of adverse childhood experiences on an urban pediatric population.

Authors:  Nadine J Burke; Julia L Hellman; Brandon G Scott; Carl F Weems; Victor G Carrion
Journal:  Child Abuse Negl       Date:  2011-06-08

4.  Urinary cortisol and six-year risk of all-cause and cardiovascular mortality.

Authors:  Nicole Vogelzangs; Aartjan T F Beekman; Yuri Milaneschi; Stefania Bandinelli; Luigi Ferrucci; Brenda W J H Penninx
Journal:  J Clin Endocrinol Metab       Date:  2010-08-25       Impact factor: 5.958

5.  Emotion regulation moderates the association between parent and child hair cortisol concentrations.

Authors:  Katie Kao; Charu T Tuladhar; Jerrold S Meyer; Amanda R Tarullo
Journal:  Dev Psychobiol       Date:  2019-04-05       Impact factor: 3.038

6.  Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse.

Authors:  Patrick O McGowan; Aya Sasaki; Ana C D'Alessio; Sergiy Dymov; Benoit Labonté; Moshe Szyf; Gustavo Turecki; Michael J Meaney
Journal:  Nat Neurosci       Date:  2009-03       Impact factor: 24.884

7.  Chronic unpredictable stress promotes neuronal apoptosis in the cerebral cortex.

Authors:  Alessia Bachis; Maria Idalia Cruz; Rachel L Nosheny; Italo Mocchetti
Journal:  Neurosci Lett       Date:  2008-07-03       Impact factor: 3.046

8.  The lifetime experience of traumatic events is associated with hair cortisol concentrations in community-based children.

Authors:  Julian G Simmons; Paul B Badcock; Sarah L Whittle; Michelle L Byrne; Lisa Mundy; George C Patton; Craig A Olsson; Nicholas B Allen
Journal:  Psychoneuroendocrinology       Date:  2015-10-19       Impact factor: 4.905

9.  Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein.

Authors:  J Boyes; A Bird
Journal:  EMBO J       Date:  1992-01       Impact factor: 11.598

10.  Gene-environment interactions between HPA-axis genes and childhood maltreatment in depression: a systematic review.

Authors:  Caroline Normann; Henriette N Buttenschøn
Journal:  Acta Neuropsychiatr       Date:  2020-01-06       Impact factor: 3.403

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