Terry P Klassen1,2,3, Stuart R Dalziel4,5,6, Franz E Babl7,8, Javier Benito9,10, Silvia Bressan11,12, James Chamberlain13,14, Todd P Chang14,15,16, Stephen B Freedman3,17, Guillermo Kohn Loncarica18,19, Mark D Lyttle20,21,22, Santiago Mintegi10,23, Rakesh D Mistry16,24, Lise E Nigrovic16,25,26, Rianne Oostenbrink12,27, Amy C Plint3,28, Pedro Rino18,19, Damian Roland22,29, Greg Van de Mosselaer30,31, Nathan Kuppermann14,32. 1. Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada. 2. Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada. 3. Pediatric Emergency Research Canada (PERC). 4. Departments of Surgery and Paediatrics: Child and Youth Health, The University of Auckland, Auckland, New Zealand. 5. Children's Emergency Department, Starship Children's Health, Auckland, New Zealand. 6. Paediatric Research in Emergency Departments International Collaborative (PREDICT). 7. Departments of Paediatrics and Critical Care, The University of Melbourne, Melbourne, Victoria, Australia. 8. Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Victoria, Australia. 9. Pediatric Emergency Department, Biocruces Bizkaia Health Research Institute, Hospital Universitario Cruces, University of the Basque Country, Bilbao, Spain. 10. Red de Investigación de la Sociedad Española de Urgencias de Pediatría/Spanish Pediatric Emergency Research Group (RISeuP/SPERG). 11. Department of Women's and Children's Health, University of Padova, Padova, Italy. 12. Research in European Pediatric Emergency Medicine (REPEM). 13. Children's National Medical Center, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA. 14. Pediatric Emergency Care Applied Research Network (PECARN). 15. Division of Emergency Medicine and Transport, Children's Hospital Los Angeles, Keck School of Medicine at University of Southern California, Los Angeles, California, USA. 16. Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics (PEM CRC). 17. Departments of Pediatrics and Emergency Medicine, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada. 18. Latin American Pediatric Emergency Medicine Society, University of Buenos Aires, Buenos Aires, Argentina. 19. Red de Investigación y Desarrollo de la Emergencia Pediátrica de Latinoamérica (RIDEPLA). 20. Emergency Department, Bristol Royal Hospital for Children, Bristol, UK. 21. Faculty of Health and Applied Sciences, University of the West of England, Bristol, UK. 22. Paediatric Emergency Research in the United Kingdom and Ireland (PERUKI). 23. Hospital Universitario Cruces, University of the Basque Country, Bilbao, Spain. 24. Department of Paediatrics, University of Colorado School of Medicine, Denver, Colorado, USA. 25. Boston Children's Hospital, Boston, Massachusetts, USA. 26. Department of Emergency Medicine, Harvard Medical School, Boston, Massachusetts, USA. 27. General Pediatrics, Erasmus University Medical Center, Rotterdam, The Netherlands. 28. Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada. 29. Children's Emergency Department, University of Leicester, Leicestershire, UK. 30. Department of Emergency Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. 31. Translating Emergency Knowledge for Kids, Winnipeg, Manitoba, Canada. 32. Departments of Emergency Medicine and Pediatrics, University of California Davis School of Medicine, Sacramento, California, USA.
Abstract
OBJECTIVES: The Pediatric Emergency Research Network (PERN) was launched in 2009 with the intent for existing national and regional research networks in paediatric emergency care to organise globally for the conduct of collaborative research across networks. METHODS: PERN has grown from five to eight member networks over the past decade. With an executive committee comprising representatives from all member networks, PERN plays a supportive and collaborative rather than governing role. The full impact of PERN's facilitation of international collaborative research, although somewhat difficult to quantify empirically, can be measured indirectly by the observed growth of the field, the nature of the increasingly challenging research questions now being addressed and the collective capacity to generate and implement new knowledge in treating acutely ill and injured children. RESULTS: Beginning as a pandemic response studying H1N1 influenza risk factors in children, PERN research has progressed to multiple observational studies and ongoing global randomised controlled trials (RCTs). As a recent example, PERN has developed sufficient network infrastructure to enable the rapid initiation of a prospective observational study in response to the current COVID-19 pandemic. CONCLUSIONS: Following its success with developing global research, the PERN goal now is to promote the implementation of scientific advances into everyday clinical practice by: (i) expanding the capacity for global RCTs; (ii) deepening the focus on implementation science; (iii) increasing attention to healthcare disparities; and (iv) expanding PERN's reach into resource-restricted regions. Through these actions, PERN aims to meet the needs of acutely ill and injured children throughout the world.
OBJECTIVES: The Pediatric Emergency Research Network (PERN) was launched in 2009 with the intent for existing national and regional research networks in paediatric emergency care to organise globally for the conduct of collaborative research across networks. METHODS: PERN has grown from five to eight member networks over the past decade. With an executive committee comprising representatives from all member networks, PERN plays a supportive and collaborative rather than governing role. The full impact of PERN's facilitation of international collaborative research, although somewhat difficult to quantify empirically, can be measured indirectly by the observed growth of the field, the nature of the increasingly challenging research questions now being addressed and the collective capacity to generate and implement new knowledge in treating acutely ill and injured children. RESULTS: Beginning as a pandemic response studying H1N1 influenza risk factors in children, PERN research has progressed to multiple observational studies and ongoing global randomised controlled trials (RCTs). As a recent example, PERN has developed sufficient network infrastructure to enable the rapid initiation of a prospective observational study in response to the current COVID-19 pandemic. CONCLUSIONS: Following its success with developing global research, the PERN goal now is to promote the implementation of scientific advances into everyday clinical practice by: (i) expanding the capacity for global RCTs; (ii) deepening the focus on implementation science; (iii) increasing attention to healthcare disparities; and (iv) expanding PERN's reach into resource-restricted regions. Through these actions, PERN aims to meet the needs of acutely ill and injured children throughout the world.
Authors: Lisa Knisley; Lisa Hartling; Mona Jabbour; David W Johnson; Eddy S Lang; Shannon MacPhee; Sarah Reid; Shannon D Scott; Doug Sinclair; Antonia S Stang; Matthieu Vincent; Terry P Klassen Journal: CJEM Date: 2021-10-08 Impact factor: 2.410
Authors: Jingxian Lan; Amy C Plint; Stuart R Dalziel; Terry P Klassen; Martin Offringa; Anna Heath Journal: Trials Date: 2022-04-11 Impact factor: 2.279