Literature DB >> 34218400

Heart failure and atrial fibrillation: new concepts in pathophysiology, management, and future directions.

Grigorios Tsigkas1, Anastasios Apostolos2, Stefanos Despotopoulos2, Georgios Vasilagkos2, Eleftherios Kallergis3, Georgios Leventopoulos2, Virginia Mplani2, Periklis Davlouros2.   

Abstract

A bidirectional pathophysiological link connects heart failure and atrial fibrillation, creating a frequent and challenging comorbidity, which includes neurohormonal hyperactivation, fibrosis development, and electrophysiologic remodeling, while they share mutual risk factors. Management for these devastating comorbidities includes most of the established treatment measures for heart failure as well as rhythm or rate control and anticoagulation mostly for atrial fibrillation, which can be achieved with either pharmaceutical or non-pharmaceutical approaches. The current manuscript aims to review the existing literature regarding the underlying pathophysiology, to present the novel trends of treatment, and to predict the future perspective of these two linked diseases with the numerous unanswered questions.
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Anticoagulation; Atrial fibrillation; Heart failure; Rate control; Rhythm control; Treatment

Mesh：

Substances：

Year:  2021        PMID： 34218400     DOI： 10.1007/s10741-021-10133-6

Source DB:  PubMed          Journal:  Heart Fail Rev        ISSN： 1382-4147            Impact factor:   4.654


  61 in total

Review 1.  Atrial fibrillation and ventricular dysfunction: a vicious electromechanical cycle.

Authors:  Yong-Mei Cha; Margaret M Redfield; Win-Kuang Shen; Bernard J Gersh
Journal:  Circulation       Date:  2004-06-15       Impact factor: 29.690

2.  Angiotensin II potentiates the slow component of delayed rectifier K+ current via the AT1 receptor in guinea pig atrial myocytes.

Authors:  Dimitar P Zankov; Mariko Omatsu-Kanbe; Takahiro Isono; Futoshi Toyoda; Wei-Guang Ding; Hiroshi Matsuura; Minoru Horie
Journal:  Circulation       Date:  2006-03-14       Impact factor: 29.690

Review 3.  Neural mechanisms of atrial arrhythmias.

Authors:  Mark J Shen; Eue-Keun Choi; Alex Y Tan; Shien-Fong Lin; Michael C Fishbein; Lan S Chen; Peng-Sheng Chen
Journal:  Nat Rev Cardiol       Date:  2011-09-27       Impact factor: 32.419

Review 4.  Atrial fibrillation in heart failure: epidemiology, pathophysiology, and rationale for therapy.

Authors:  William H Maisel; Lynne Warner Stevenson
Journal:  Am J Cardiol       Date:  2003-03-20       Impact factor: 2.778

5.  Relation of the renin-angiotensin-aldosterone system to clinical state in congestive heart failure.

Authors:  V J Dzau; W S Colucci; N K Hollenberg; G H Williams
Journal:  Circulation       Date:  1981-03       Impact factor: 29.690

6.  Prognostic relevance of atrial fibrillation in patients with chronic heart failure on long-term treatment with beta-blockers: results from COMET.

Authors:  Karl Swedberg; Lars G Olsson; Andrew Charlesworth; John Cleland; Peter Hanrath; Michel Komajda; Marco Metra; Christian Torp-Pedersen; Philip Poole-Wilson
Journal:  Eur Heart J       Date:  2005-03-14       Impact factor: 29.983

7.  Atrial fibrillation and risk of clinical events in chronic heart failure with and without left ventricular systolic dysfunction: results from the Candesartan in Heart failure-Assessment of Reduction in Mortality and morbidity (CHARM) program.

Authors:  Lars G Olsson; Karl Swedberg; Anique Ducharme; Christopher B Granger; Eric L Michelson; John J V McMurray; Margareta Puu; Salim Yusuf; Marc A Pfeffer
Journal:  J Am Coll Cardiol       Date:  2006-04-27       Impact factor: 24.094

8.  The heart failure pandemic: The clinical and economic burden in Greece.

Authors:  P Stafylas; D Farmakis; G Kourlaba; G Giamouzis; K Tsarouhas; N Maniadakis; J Parissis
Journal:  Int J Cardiol       Date:  2016-10-17       Impact factor: 4.164

9.  The effect of atrial dilatation on the genesis of atrial arrhythmias.

Authors:  F Solti; T Vecsey; V Kékesi; A Juhász-Nagy
Journal:  Cardiovasc Res       Date:  1989-10       Impact factor: 10.787

Review 10.  Renin-angiotensin-system inhibition in the context of corona virus disease-19: experimental evidence, observational studies, and clinical implications.

Authors:  Filippos Triposkiadis; Randall C Starling; Andrew Xanthopoulos; Javed Butler; Harisios Boudoulas
Journal:  Heart Fail Rev       Date:  2020-09-01       Impact factor: 4.214
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  3 in total

Review 1.  NR4A3: A Key Nuclear Receptor in Vascular Biology, Cardiovascular Remodeling, and Beyond.

Authors:  José Martínez-González; Laia Cañes; Judith Alonso; Carme Ballester-Servera; Antonio Rodríguez-Sinovas; Irene Corrales; Cristina Rodríguez
Journal:  Int J Mol Sci       Date:  2021-10-21       Impact factor: 5.923

2.  Prognostic Impact and Predictors of New-Onset Atrial Fibrillation in Heart Failure.

Authors:  Hyo-In Choi; Sang Eun Lee; Min-Seok Kim; Hae-Young Lee; Hyun-Jai Cho; Jin Oh Choi; Eun-Seok Jeon; Kyung-Kuk Hwang; Shung Chull Chae; Sang Hong Baek; Seok-Min Kang; Dong-Ju Choi; Byung-Su Yoo; Kye Hun Kim; Myeong-Chan Cho; Byung-Hee Oh; Jae-Joong Kim
Journal:  Life (Basel)       Date:  2022-04-13

Review 3.  Dyspnea in patients with atrial fibrillation: Mechanisms, assessment and an interdisciplinary and integrated care approach.

Authors:  Rachel M J van der Velden; Astrid N L Hermans; Nikki A H A Pluymaekers; Monika Gawalko; Adrian Elliott; Jeroen M Hendriks; Frits M E Franssen; Annelies M Slats; Vanessa P M van Empel; Isabelle C Van Gelder; Dick H J Thijssen; Thijs M H Eijsvogels; Carsten Leue; Harry J G M Crijns; Dominik Linz; Sami O Simons
Journal:  Int J Cardiol Heart Vasc       Date:  2022-07-19
  3 in total

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