Literature DB >> 34215365

Interferons in Systemic Lupus Erythematosus.

Sirisha Sirobhushanam1, Stephanie Lazar1, J Michelle Kahlenberg2.   

Abstract

Skewing of type I interferon (IFN) production and responses is a hallmark of systemic lupus erythematosus (SLE). Genetic and environmental contributions to IFN production lead to aberrant innate and adaptive immune activation even before clinical development of disease. Basic and translational research in this arena continues to identify contributions of IFNs to disease pathogenesis, and several promising therapeutic options for targeting of type I IFNs and their signaling pathways are in development for treatment of SLE patients.
Copyright © 2021 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Interferon; JAK; Lupus; STAT

Mesh：

Substances：

Year:  2021        PMID： 34215365      PMCID： PMC8254852          DOI： 10.1016/j.rdc.2021.04.001

Source DB:  PubMed          Journal:  Rheum Dis Clin North Am        ISSN： 0889-857X            Impact factor:   2.032


  141 in total

Review 1.  Understanding Human Autoimmunity and Autoinflammation Through Transcriptomics.

Authors:  Romain Banchereau; Alma-Martina Cepika; Jacques Banchereau; Virginia Pascual
Journal:  Annu Rev Immunol       Date:  2017-01-30       Impact factor: 28.527

2.  Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification.

Authors:  Melissa E Munroe; Rufei Lu; Yan D Zhao; Dustin A Fife; Julie M Robertson; Joel M Guthridge; Timothy B Niewold; George C Tsokos; Michael P Keith; John B Harley; Judith A James
Journal:  Ann Rheum Dis       Date:  2016-01-25       Impact factor: 19.103

3.  The antiviral cytokines IFN-α and IFN-β modulate parietal epithelial cells and promote podocyte loss: implications for IFN toxicity, viral glomerulonephritis, and glomerular regeneration.

Authors:  Adriana Migliorini; Maria L Angelotti; Shrikant R Mulay; Onkar O Kulkarni; Jana Demleitner; Alexander Dietrich; Costanza Sagrinati; Lara Ballerini; Anna Peired; Stuart J Shankland; Helen Liapis; Paola Romagnani; Hans-Joachim Anders
Journal:  Am J Pathol       Date:  2013-06-05       Impact factor: 4.307

4.  Interferon signature gene expression is correlated with autoantibody profiles in patients with incomplete lupus syndromes.

Authors:  Q-Z Li; J Zhou; Y Lian; B Zhang; V K Branch; F Carr-Johnson; D R Karp; C Mohan; E K Wakeland; N J Olsen
Journal:  Clin Exp Immunol       Date:  2009-12-01       Impact factor: 4.330

5.  The pathogenesis of autoimmunity in New Zealand mice, I. Induction of antinucleic acid antibodies by polyinosinic-polycytidylic acid.

Authors:  A D Steinberg; S Baron; N Talal
Journal:  Proc Natl Acad Sci U S A       Date:  1969-08       Impact factor: 11.205

6.  Type I interferons are associated with subclinical markers of cardiovascular disease in a cohort of systemic lupus erythematosus patients.

Authors:  Emily C Somers; Wenpu Zhao; Emily E Lewis; Lu Wang; Jeffrey J Wing; Baskaran Sundaram; Ella A Kazerooni; W Joseph McCune; Mariana J Kaplan
Journal:  PLoS One       Date:  2012-05-14       Impact factor: 3.240

7.  Anifrolumab, an Anti-Interferon-α Receptor Monoclonal Antibody, in Moderate-to-Severe Systemic Lupus Erythematosus.

Authors:  Richard Furie; Munther Khamashta; Joan T Merrill; Victoria P Werth; Kenneth Kalunian; Philip Brohawn; Gabor G Illei; Jorn Drappa; Liangwei Wang; Stephen Yoo
Journal:  Arthritis Rheumatol       Date:  2017-02       Impact factor: 10.995

8.  Presence of an interferon signature in individuals who are anti-nuclear antibody positive lacking a systemic autoimmune rheumatic disease diagnosis.

Authors:  Joan Wither; Sindhu R Johnson; Tony Liu; Babak Noamani; Dennisse Bonilla; Larissa Lisnevskaia; Earl Silverman; Arthur Bookman; Carolina Landolt-Marticorena
Journal:  Arthritis Res Ther       Date:  2017-02-28       Impact factor: 5.156

9.  Prediction of autoimmune connective tissue disease in an at-risk cohort: prognostic value of a novel two-score system for interferon status.

Authors:  Md Yuzaiful Md Yusof; Antonios Psarras; Yasser M El-Sherbiny; Elizabeth M A Hensor; Katherine Dutton; Sabih Ul-Hassan; Ahmed S Zayat; Mohammad Shalbaf; Adewonuola Alase; Miriam Wittmann; Paul Emery; Edward M Vital
Journal:  Ann Rheum Dis       Date:  2018-06-21       Impact factor: 27.973

10.  Whole-genome sequencing identifies complex contributions to genetic risk by variants in genes causing monogenic systemic lupus erythematosus.

Authors:  Jonas Carlsson Almlöf; Sara Nystedt; Dag Leonard; Maija-Leena Eloranta; Giorgia Grosso; Christopher Sjöwall; Anders A Bengtsson; Andreas Jönsen; Iva Gunnarsson; Elisabet Svenungsson; Lars Rönnblom; Johanna K Sandling; Ann-Christine Syvänen
Journal:  Hum Genet       Date:  2019-02-01       Impact factor: 4.132
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  1 in total

1.  The Type I Interferon Pathway Is Upregulated in the Cutaneous Lesions and Blood of Multibacillary Leprosy Patients With Erythema Nodosum Leprosum.

Authors:  Thabatta Leal Silveira Andrezo Rosa; Mayara Abud Mendes; Natasha Ribeiro Cardoso Linhares; Thais Fernanda Rodrigues; André Alves Dias; Thyago Leal-Calvo; Mariana Gandini; Helen Ferreira; Fabrício da Mota Ramalho Costa; Anna Maria Sales; Thaís Porto Amadeu; Veronica Schmitz; Roberta Olmo Pinheiro; Luciana Silva Rodrigues; Milton Ozório Moraes; Maria Cristina Vidal Pessolani
Journal:  Front Med (Lausanne)       Date:  2022-06-06
  1 in total

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