Literature DB >> 34214438

Building and destroying synaptic bridges: How do Hevin/Sparcl1, SPARC, and MDGAs modify trans-synaptic neurexin-neuroligin interactions?

Juan J Ramirez1, Dhanesh Sivadasan Bindu2, Cagla Eroglu3.   

Abstract

Astrocyte-secreted Hevin induces synapse formation by bridging the trans-synaptic organizers, neuroligins and neurexins. In this issue of Structure, Fan et al. (2021) elucidate the structural basis of Hevin's interaction with these molecules and reveal the competitive interplay between Hevin, SPARC, and MDGAs.
Copyright © 2021 Elsevier Ltd. All rights reserved.

Entities:  

Year:  2021        PMID： 34214438     DOI： 10.1016/j.str.2021.06.011

Source DB:  PubMed          Journal:  Structure        ISSN： 0969-2126            Impact factor:   5.006


  1 in total

1.  A neurogenic signature involving monoamine Oxidase-A controls human thermogenic adipose tissue development.

Authors:  Javier Solivan-Rivera; Zinger Yang Loureiro; Tiffany DeSouza; Anand Desai; Sabine Pallat; Qin Yang; Raziel Rojas-Rodriguez; Rachel Ziegler; Pantos Skritakis; Shannon Joyce; Denise Zhong; Tammy Nguyen; Silvia Corvera
Journal:  Elife       Date:  2022-09-15       Impact factor: 8.713
  1 in total

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