Literature DB >> 34202172

Uncovering Signals from the Coronavirus Genome.

Enrique Canessa1.   

Abstract

A signal analysis of the complete genome sequenced for coronavirus variants of concern-B.1.1.7 (Alpha), B.1.135 (Beta) and P1 (Gamma)-and coronavirus variants of interest-B.1.429-B.1.427 (Epsilon) and B.1.525 (Eta)-is presented using open GISAID data. We deal with a certain new type of finite alternating sum series having independently distributed terms associated with binary (0,1) indicators for the nucleotide bases. Our method provides additional information to conventional similarity comparisons via alignment methods and Fourier Power Spectrum approaches. It leads to uncover distinctive patterns regarding the intrinsic data organization of complete genomics sequences according to its progression along the nucleotide bases position. The present new method could be useful for the bioinformatics surveillance and dynamics of coronavirus genome variants.

Entities:  

Keywords:  SARS-CoV-2; alternating series; comparative genomics variants; sequence analysis

Mesh:

Substances:

Year:  2021        PMID: 34202172     DOI: 10.3390/genes12070973

Source DB:  PubMed          Journal:  Genes (Basel)        ISSN: 2073-4425            Impact factor:   4.096


  14 in total

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Authors: 
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Authors:  Norbert Pardi; Michael J Hogan; Frederick W Porter; Drew Weissman
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Journal:  J Virol       Date:  2015-12-30       Impact factor: 5.103

5.  Modeling of body mass index by Newton's second law.

Authors:  Enrique Canessa
Journal:  J Theor Biol       Date:  2007-06-16       Impact factor: 2.691

6.  A pneumonia outbreak associated with a new coronavirus of probable bat origin.

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Journal:  Nature       Date:  2020-02-03       Impact factor: 69.504

7.  Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.

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Review 9.  The spike protein of SARS-CoV--a target for vaccine and therapeutic development.

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10.  Application of discrete Fourier inter-coefficient difference for assessing genetic sequence similarity.

Authors:  Brian R King; Maurice Aburdene; Alex Thompson; Zach Warres
Journal:  EURASIP J Bioinform Syst Biol       Date:  2014-05-28
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  3 in total

1.  GenomeBits insight into omicron and delta variants of coronavirus pathogen.

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3.  Wave-like behaviour in (0,1) binary sequences.

Authors:  Enrique Canessa
Journal:  Sci Rep       Date:  2022-08-17       Impact factor: 4.996

  3 in total

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