Literature DB >> 34201007

Bispecific T Cell Engagers for the Treatment of Multiple Myeloma: Achievements and Challenges.

Kinan Alhallak1,2, Jennifer Sun1,2, Amanda Jeske1,2, Chaelee Park1, Jessica Yavner1, Hannah Bash1, Berit Lubben1, Ola Adebayo1, Ayah Khaskiah3, Abdel Kareem Azab1,2.   

Abstract

MM is the second most common hematological malignancy and represents approximately 20% of deaths from hematopoietic cancers. The advent of novel agents has changed the therapeutic landscape of MM treatment; however, MM remains incurable. T cell-based immunotherapy such as BTCEs is a promising modality for the treatment of MM. This review article discusses the advancements and future directions of BTCE treatments for MM.

Entities:  

Keywords:  bispecific T cell engagers; chimeric antigen receptor-T cells; multiple myeloma

Year:  2021        PMID: 34201007     DOI: 10.3390/cancers13122853

Source DB:  PubMed          Journal:  Cancers (Basel)        ISSN: 2072-6694            Impact factor:   6.639


  1 in total

1.  Cancer drug resistance in multiple myeloma.

Authors:  Fatih M Uckun
Journal:  Cancer Drug Resist       Date:  2022-03-25
  1 in total

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