Literature DB >> 34194647

Clinical Outcomes and Global Health After Joint Debridement in Adult-Onset Septic Arthritis: A Prospective Observational Study.

Ranjith Malipeddi1, Sandeep Kumar Nema1, B Gopisankar1, M Prabu1, P Pasupathy1, B Suresh Gandhi1.   

Abstract

PURPOSE: Despite several reports on risk factors for septic arthritis (SA) in adults, the outcomes on quality of life and joint function are sparsely reported. This study aimed to investigate the quality of life and joint function in adult patients treated for SA.
METHODS: This prospective observational study enrolled clinically diagnosed adult SA patients and estimated Euroqol 5-dimension 5 levels (EQ-5D-5L) questionnaire, Euroqol Visual Analog Scale (EQ-VAS) and a validated tool for joint function at 1, 3, 6 and 12 months after debridement.
RESULTS: Twenty seven patients (20 males/7 females) with 21 knees, four shoulders, and two elbows were evaluated. The mean age of the cases was 51(± 13.00) years. Three cases sustained mortality. EQ-5D-5L (P < 0.01) and EQ-VAS (P < 0.01) scores improved significantly between all time frames. Mean Knee society (P < 0.01), Shoulder QuickDASH, and Mayo elbow scores improved at all time frames. There was no difference in primary outcomes between early (< 14 days) and late (14 days or more) presentation. There was no difference in primary outcome measures between confirmed and suspected SA. Fifteen patients could ambulate without support, while 6 needed some support for walking at 1 year.
CONCLUSION: Improved outcomes can be expected in quality of life and joint function in adults' septic arthritis at the end of 1 year after surgical treatment; however, the effects of delay in presentation need to be investigated further. Isolation of the microorganism from an infected joint has no bearing on the outcome measures. © Indian Orthopaedics Association 2021.

Entities:  

Keywords:  C-reactive protein; EuroQol; Functional outcome; Knee society score; Morbidity; Mortality; Prognosis; Quality of life; Risk factors; Septic arthritis

Year:  2021        PMID: 34194647      PMCID: PMC8192621          DOI: 10.1007/s43465-021-00389-3

Source DB:  PubMed          Journal:  Indian J Orthop        ISSN: 0019-5413            Impact factor:   1.251


  22 in total

1.  Microbiological profile of septic arthritis in adults: Lessons learnt and treatment strategies.

Authors:  Jerry George; V J Chandy; John Premnath; T D Hariharan; Anil Thomas Oommen; V Balaji; Pradeep M Poonnoose
Journal:  Indian J Med Microbiol       Date:  2019 Jan-Mar       Impact factor: 0.985

2.  Management of septic arthritis: a systematic review.

Authors:  C J Mathews; G Kingsley; M Field; A Jones; V C Weston; M Phillips; D Walker; G Coakley
Journal:  Postgrad Med J       Date:  2008-05       Impact factor: 2.401

3.  Analysis of mortality in a cohort of 650 cases of bacteremic osteoarticular infections.

Authors:  Joan Gomez-Junyent; Oscar Murillo; Imma Grau; Eva Benavent; Alba Ribera; Xavier Cabo; Fe Tubau; Javier Ariza; Roman Pallares
Journal:  Semin Arthritis Rheum       Date:  2018-01-31       Impact factor: 5.532

4.  Septic arthritis of the knee in adults: treatment by arthroscopy or arthrotomy.

Authors:  D C Wirtz; M Marth; O Miltner; U Schneider; K W Zilkens
Journal:  Int Orthop       Date:  2001       Impact factor: 3.075

5.  The outcome of bacterial arthritis: a prospective community-based study.

Authors:  C J Kaandorp; P Krijnen; H J Moens; J D Habbema; D van Schaardenburg
Journal:  Arthritis Rheum       Date:  1997-05

6.  Recent trends in adult-onset septic arthritis of the knee and hip: retrospective analysis of patients treated during the past 50 years.

Authors:  Toru Okano; Makoto Enokida; Ryoji Otsuki; Hiroshi Hagino; Ryota Teshima
Journal:  J Infect Chemother       Date:  2011-05-17       Impact factor: 2.211

7.  Outcomes of paediatric septic arthritis of the hip and knee at 1-20 years in an Australian urban centre.

Authors:  Roseanna L Hoswell; Brenton P Johns; Mark R Loewenthal; David C Dewar
Journal:  ANZ J Surg       Date:  2019-04-08       Impact factor: 1.872

8.  A prospective study of the incidence and characteristics of septic arthritis in a teaching hospital in Riyadh, Saudi Arabia.

Authors:  Abdurahman Saud Al Arfaj
Journal:  Clin Rheumatol       Date:  2008-06-27       Impact factor: 2.980

9.  Prospective comparative study of patients with culture proven and high suspicion of adult onset septic arthritis.

Authors:  M N Gupta; R D Sturrock; M Field
Journal:  Ann Rheum Dis       Date:  2003-04       Impact factor: 19.103

10.  Morbimortality in adult patients with septic arthritis: a three-year hospital-based study.

Authors:  Julien Ferrand; Youssef El Samad; Benoit Brunschweiler; Franck Grados; Nassima Dehamchia-Rehailia; Alice Séjourne; Jean-Luc Schmit; Antoine Gabrion; Patrice Fardellone; Julien Paccou
Journal:  BMC Infect Dis       Date:  2016-06-01       Impact factor: 3.090

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