Literature DB >> 34194637

An Overview of Decision Making in the Management of Metastatic Spinal Tumors.

Gautam R Zaveri1, Reetu Jain2, Nishank Mehta3, Bhavuk Garg3.   

Abstract

INTRODUCTION: Spinal metastases are the most commonly encountered spinal tumors. With increasing life expectancy and better systemic treatment options, the incidence of patients seeking treatment for spinal metastasis is rising. Radical resections and conventional low-dose radiotherapy have given way to modern 'separation' surgeries and stereotactic body radiotherapy which entails lesser morbidity and improved local control. This article provides an overview of the decision making and currently available treatment options for metastatic spinal tumors.
METHODS: A MEDLINE literature search was made for studies in English language reporting on human subjects, describing results of various treatment options that are a part of multidisciplinary management of metastatic spinal tumors. The highest-quality evidence available in the literature was reviewed. DISCUSSION: Treatment of patients with metastatic spinal tumors is largely palliative, with radiotherapy and selective surgery being the mainstays of management. Multidisciplinary management that incorporates factors like patient performance status, expected survival and systemic burden of disease and employs well-validated decision-making frameworks for guiding treatment holds the key to an effective palliative treatment strategy. Effective pain management, achieving local control, adequate neurological decompression in the setting of epidural cord compression and surgical stabilization for mechanical stabilization are the main goals of treatment.
CONCLUSION: The management of metastatic spinal tumors has been rapidly evolving; currently, limited decompression and stabilization followed by postoperative SBRT for local tumor control are associated with less morbidity and may be referred to as the current standard of care in these patients. © Indian Orthopaedics Association 2021.

Entities:  

Keywords:  Decision-making algorithm; Separation surgery; Spinal metastases; Stereotactic body radiotherapy

Year:  2021        PMID: 34194637      PMCID: PMC8192670          DOI: 10.1007/s43465-021-00368-8

Source DB:  PubMed          Journal:  Indian J Orthop        ISSN: 0019-5413            Impact factor:   1.251


  74 in total

1.  Reliability analysis of the epidural spinal cord compression scale.

Authors:  Mark H Bilsky; Ilya Laufer; Daryl R Fourney; Michael Groff; Meic H Schmidt; Peter Paul Varga; Frank D Vrionis; Yoshiya Yamada; Peter C Gerszten; Timothy R Kuklo
Journal:  J Neurosurg Spine       Date:  2010-09

2.  Selecting treatment for patients with malignant epidural spinal cord compression-does age matter?: results from a randomized clinical trial.

Authors:  John H Chi; Ziya Gokaslan; Paul McCormick; Phillip A Tibbs; Richard J Kryscio; Roy A Patchell
Journal:  Spine (Phila Pa 1976)       Date:  2009-03-01       Impact factor: 3.468

3.  Surgery improves pain, function and quality of life in patients with spinal metastases: a prospective study on 118 patients.

Authors:  Gerald M Y Quan; Jean-Marc Vital; Nicholas Aurouer; Ibrahim Obeid; Jean Palussière; Abou Diallo; Vincent Pointillart
Journal:  Eur Spine J       Date:  2011-06-26       Impact factor: 3.134

4.  The NOMS framework: approach to the treatment of spinal metastatic tumors.

Authors:  Ilya Laufer; David G Rubin; Eric Lis; Brett W Cox; Michael D Stubblefield; Yoshiya Yamada; Mark H Bilsky
Journal:  Oncologist       Date:  2013-05-24

5.  Spinal instability as defined by the spinal instability neoplastic score is associated with radiotherapy failure in metastatic spinal disease.

Authors:  Merel Huisman; Joanne M van der Velden; Marco van Vulpen; Maurice A A J van den Bosch; Edward Chow; F Cumhur Öner; Albert Yee; Helena M Verkooijen; Jorrit-Jan Verlaan
Journal:  Spine J       Date:  2014-04-04       Impact factor: 4.166

Review 6.  Metastatic spine tumors.

Authors:  John K Ratliff; Paul R Cooper
Journal:  South Med J       Date:  2004-03       Impact factor: 0.954

7.  Surgery for solitary metastases of the spine: rationale and results of treatment.

Authors:  Narayan Sundaresan; Allen Rothman; Karen Manhart; Kevin Kelliher
Journal:  Spine (Phila Pa 1976)       Date:  2002-08-15       Impact factor: 3.468

8.  The Effect of Perioperative Radiation Therapy on Spinal Bone Fusion Following Spine Tumor Surgery.

Authors:  Tae-Kyum Kim; Wonik Cho; Sang Min Youn; Ung-Kyu Chang
Journal:  J Korean Neurosurg Soc       Date:  2016-10-24

9.  Neurological Outcome Following Surgical Treatment of Spinal Metastases.

Authors:  Abdelaal Abdelbaky; Hazem Eltahawy
Journal:  Asian J Neurosurg       Date:  2018 Apr-Jun

10.  Epidemiological Characteristics of 1196 Patients with Spinal Metastases: A Retrospective Study.

Authors:  Feng Wang; Hao Zhang; Li Yang; Xiong-Gang Yang; Hao-Ran Zhang; Ji-Kai Li; Rui-Qi Qiao; Yong-Cheng Hu
Journal:  Orthop Surg       Date:  2019-11-22       Impact factor: 2.071

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