Rüdiger E Scharf1,2,3, Lorenzo Alberio4. 1. Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, Massachusetts, USA. 2. Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA. 3. Division of Experimental and Clinical Hemostasis, Hemotherapy, and Transfusion Medicine, and Hemophilia Comprehensive Care Center, Institute of Transplantation Diagnostics and Cell Therapy, Heinrich Heine University Medical Center, Düsseldorf, Germany. 4. Division of Hematology and Central Hematology Laboratory, University Hospital of Lausanne, Lausanne, Switzerland.