Literature DB >> 3419082

Fibronectin decrease in liver cirrhosis is related to spleen size.

V de Angelis1, M Zambon, L Toffolo, C Donada, G L Molaro, R Zuin.   

Abstract

We found a significantly lower plasma fibronectin concentration in cirrhotic patients than in controls, a significant inverse relationship between fibronectin and spleen size, but no correlation between fibronectin and hepatic blood flow, prothrombin time, or serum albumin. We suggest that the increased degradation in the enlarged spleen is more relevant than the decreased synthesis in reducing plasma fibronectin levels during liver cirrhosis with portal hypertension.

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Year:  1988        PMID： 3419082     DOI： 10.1007/BF01736520

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN： 0023-2173


  17 in total

1.  The use of indocyanine green in the measurement of hepatic blood flow and as a test of hepatic function.

Authors:  J CAESAR; S SHALDON; L CHIANDUSSI; L GUEVARA; S SHERLOCK
Journal:  Clin Sci       Date:  1961-08       Impact factor: 6.124

2.  Immunochemical quantitation of antigens by single radial immunodiffusion.

Authors:  G Mancini; A O Carbonara; J F Heremans
Journal:  Immunochemistry       Date:  1965-09

3.  Prognostic value of serum fibronectin concentration in alcoholic cirrhotic patients.

Authors:  S Naveau; T Poynard; A Abella; J P Pignon; A Poitrine; H Agostini; O Zourabichvili; J C Chaput
Journal:  Hepatology       Date:  1985 Sep-Oct       Impact factor: 17.425

4.  Low fibronectin in portal hypertension.

Authors:  P N Foster; M Bowen; P D Howdle; M S Losowsky
Journal:  Digestion       Date:  1983       Impact factor: 3.216

5.  Plasma fibronectin is synthesized and secreted by hepatocytes.

Authors:  J W Tamkun; R O Hynes
Journal:  J Biol Chem       Date:  1983-04-10       Impact factor: 5.157

6.  Cross-linking of cold-insoluble globulin by fibrin-stabilizing factor.

Authors:  D F Mosher
Journal:  J Biol Chem       Date:  1975-08-25       Impact factor: 5.157

7.  Plasma fibronectin levels in clinical disease states and after cryoprecipitate infusion.

Authors:  M V Ragni; J H Lewis; J A Spero; F A Bontempo
Journal:  Thromb Haemost       Date:  1984-12-29       Impact factor: 5.249

8.  Clinical studies on plasma fibronectin and factor XIII; with special reference to hyperlipoproteinemia.

Authors:  M Cucuianu; H G Rus; A Cristea; F Niculescu; D Bedeleanu; D Poruţiu; S Roman
Journal:  Clin Chim Acta       Date:  1985-04-30       Impact factor: 3.786

9.  Fibronectin is produced by human macrophages.

Authors:  K Alitalo; T Hovi; A Vaheri
Journal:  J Exp Med       Date:  1980-03-01       Impact factor: 14.307

10.  Synthesis of fibronectin by cultured human endothelial cells.

Authors:  E A Jaffe; D F Mosher
Journal:  J Exp Med       Date:  1978-06-01       Impact factor: 14.307
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