| Literature DB >> 34189948 |
Bangyu Luo1, Jixi Li1, Xianhua Hou2, Qiao Yang3, Yi Zhou1, Jun Ye4, Xiaocheng Wu5, Yimei Feng6, Tianyu Hu7, Zhi Xu8, Ying He9, Jianguo Sun1.
Abstract
The novel coronavirus disease 2019 (COVID-19) pandemic has lasted over 1 year and will not disappear in a short time. There is no specific remedy against the virus as yet. Vaccination is thus far one of the most important strategies for preventing COVID-19. Cancer patients with COVID-19 have a higher mortality because of immunosuppression. Immune checkpoint inhibitors (ICIs) are a novel anticancer strategy for blocking inhibitory pathways, which are related to the immune response. There is a question regarding whether COVID-19 vaccination and ICI treatment impact each other in cancer patients. This review explores both sides of the relationship between ICI treatment and COVID-19 vaccination and suggests good efficacy and safety of ICI treatment after COVID-19 vaccination as well as little impact on the virus protection and toxicity associated with COVID-19 vaccination during ICI treatment.Entities:
Keywords: COVID-19; cancer; efficacy; immune checkpoint inhibitor; vaccination
Year: 2021 PMID: 34189948 DOI: 10.2217/fon-2021-0288
Source DB: PubMed Journal: Future Oncol ISSN: 1479-6694 Impact factor: 3.404