Literature DB >> 34189647

The BEAF-32 Protein Directly Interacts with Z4/putzig and Chriz/Chromator Proteins in Drosophila melanogaster.

L S Melnikova1, V V Molodina2, M V Kostyuchenko2, P G Georgiev2, A K Golovnin2.   

Abstract

In Drosophila, the BEAF-32, Z4/putzig, and Chriz/Chromator proteins colocalize in the interbands of polytene chromosomes. It was assumed that these proteins can form a complex that affects the structure of chromatin. However, the mechanism of the formation of such a complex has not been studied. We have proved for the first time that the BEAF-32, Z4/putzig, and Chriz/Chromator proteins interact directly with each other and localized the protein domains that provide multiple protein-protein interactions. Based on the data obtained, we developed a model of the mechanism of the formation the BEAF/Z4/Chriz complex and its recruitment to chromatin.

Entities:  

Keywords:  BEAF-32; Chriz/Chromator; Z4/putzig; protein–protein interaction; yeast two-hybrid system

Year:  2021        PMID： 34189647     DOI： 10.1134/S1607672921030066

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


  13 in total

1.  The Chriz-Z4 complex recruits JIL-1 to polytene chromosomes, a requirement for interband-specific phosphorylation of H3S10.

Authors:  Miao Gan; Selina Moebus; Harald Eggert; Harald Saumweber
Journal:  J Biosci       Date:  2011-08       Impact factor: 1.826

2.  The Drosophila boundary element-associated factors BEAF-32A and BEAF-32B affect chromatin structure.

Authors:  Matthew K Gilbert; Yian Yee Tan; Craig M Hart
Journal:  Genetics       Date:  2006-04-30       Impact factor: 4.562

3.  The Chriz Protein Promotes the Recruitment of the Z4 Protein to the STAT-Dependent Promoters.

Authors:  L S Melnikova; M V Kostyuchenko; P G Georgiev; A K Golovnin
Journal:  Dokl Biochem Biophys       Date:  2020-04-27       Impact factor: 0.788

4.  Chriz, a chromodomain protein specific for the interbands of Drosophila melanogaster polytene chromosomes.

Authors:  A A Gortchakov; H Eggert; M Gan; J Mattow; I F Zhimulev; H Saumweber
Journal:  Chromosoma       Date:  2005-04-09       Impact factor: 4.316

5.  Characterization of BEAF mutations isolated by homologous recombination in Drosophila.

Authors:  Swarnava Roy; Matthew K Gilbert; Craig M Hart
Journal:  Genetics       Date:  2007-04-15       Impact factor: 4.562

6.  Identification of the Drosophila interband-specific protein Z4 as a DNA-binding zinc-finger protein determining chromosomal structure.

Authors:  Harald Eggert; Andrej Gortchakov; Harald Saumweber
Journal:  J Cell Sci       Date:  2004-08-03       Impact factor: 5.285

7.  A novel Pzg-NURF complex regulates Notch target gene activity.

Authors:  Sabrina J Kugler; Anja C Nagel
Journal:  Mol Biol Cell       Date:  2010-08-04       Impact factor: 4.138

8.  Visualization of chromosomal domains with boundary element-associated factor BEAF-32.

Authors:  K Zhao; C M Hart; U K Laemmli
Journal:  Cell       Date:  1995-06-16       Impact factor: 41.582

9.  The NSL complex regulates housekeeping genes in Drosophila.

Authors:  Kin Chung Lam; Friederike Mühlpfordt; Juan M Vaquerizas; Sunil Jayaramaiah Raja; Herbert Holz; Nicholas M Luscombe; Thomas Manke; Asifa Akhtar
Journal:  PLoS Genet       Date:  2012-06-14       Impact factor: 5.917

10.  BEAF regulates cell-cycle genes through the controlled deposition of H3K9 methylation marks into its conserved dual-core binding sites.

Authors:  Eldon Emberly; Roxane Blattes; Bernd Schuettengruber; Magali Hennion; Nan Jiang; Craig M Hart; Emmanuel Käs; Olivier Cuvier
Journal:  PLoS Biol       Date:  2008-12-23       Impact factor: 8.029
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