Literature DB >> 34187178

Mobile Stroke Units Facilitate Prehospital Management of Intracerebral Hemorrhage.

S Regan Cooley1, Henry Zhao1,2, Bruce C V Campbell1,2, Leonid Churilov1,3, Skye Coote1, Damien Easton1, Francesca Langenberg1,4, Michael Stephenson2, Bernard Yan1, Patricia M Desmond4, Peter J Mitchell4, Mark W Parsons1, Geoffrey A Donnan1, Stephen M Davis1, Nawaf Yassi1,5.   

Abstract

Background and Purpose: Mobile stroke units (MSUs) improve reperfusion therapy times in acute ischemic stroke (AIS). However, prehospital management options for intracerebral hemorrhage (ICH) are less established. We describe the initial Melbourne MSU experience in ICH.
Methods: Consecutive patients with ICH and AIS treated by the Melbourne MSU were included. We describe demographics, proportions of patients receiving specific therapies, and bypass to comprehensive/neurosurgical centers. We also compare operational time metrics between patients with MSU-ICH and MSU-AIS.
Results: During a 2-year period, the Melbourne MSU managed 49 patients with ICH, mean (SD) age 74 (12) years, median (interquartile range) National Institutes of Health Stroke Scale 17 (12–20). Intravenous antihypertensives were the commonest treatment provided (46.9%). Bypass of a primary center to a comprehensive center with neurosurgical expertise occurred in 32.7% of patients with MSU-ICH compared with 20.5% of patients with MSU-AIS. Compared with patients with MSU-AIS, patients with MSU-ICH had faster onset-to-emergency-call, and onset-to-scene-arrival times at the median and 75th percentiles. Conclusions: MSUs can facilitate ultra-early ICH diagnosis, management, and triage.

Entities:  

Keywords:  benchmarking; cerebral hemorrhage; demographics; reatment; triage

Mesh:

Substances:

Year:  2021        PMID: 34187178     DOI: 10.1161/STROKEAHA.121.034592

Source DB:  PubMed          Journal:  Stroke        ISSN: 0039-2499            Impact factor:   7.914


  4 in total

Review 1.  Mobile Stroke Units: Current Evidence and Impact.

Authors:  Praveen Hariharan; Muhammad Bilal Tariq; James C Grotta; Alexandra L Czap
Journal:  Curr Neurol Neurosci Rep       Date:  2022-02-07       Impact factor: 5.081

2.  European Stroke Organisation (ESO) guidelines on mobile stroke units for prehospital stroke management.

Authors:  Silke Walter; Heinrich J Audebert; Aristeidis H Katsanos; Karianne Larsen; Simona Sacco; Thorsten Steiner; Guillaume Turc; Georgios Tsivgoulis
Journal:  Eur Stroke J       Date:  2022-02-09

3.  Tenecteplase versus Alteplase for Stroke Thrombolysis Evaluation Trial in the Ambulance (Mobile Stroke Unit-TASTE-A): protocol for a prospective randomised, open-label, blinded endpoint, phase II superiority trial of tenecteplase versus alteplase for ischaemic stroke patients presenting within 4.5 hours of symptom onset to the mobile stroke unit.

Authors:  Andrew Bivard; Henry Zhao; Skye Coote; Bruce Campbell; Leonid Churilov; Nawaf Yassi; Bernard Yan; Michael Valente; Angelos Sharobeam; Anna Balabanski; Angela Dos Santos; Felix Ng; Francesca Langenberg; Michael Stephenson; Karen Smith; Steve Bernard; Vincent Thijs; Geoffrey Cloud; Philip Choi; Henry Ma; Tissa Wijeratne; Chushuang Chen; Liudmyla Olenko; Stephen M Davis; Geoffrey A Donnan; Mark Parsons
Journal:  BMJ Open       Date:  2022-04-29       Impact factor: 3.006

4.  Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase II randomised placebo-controlled double-blind multicentre trial.

Authors:  Geoffrey A Donnan; Stephen M Davis; Nawaf Yassi; Henry Zhao; Leonid Churilov; Bruce C V Campbell; Teddy Wu; Henry Ma; Andrew Cheung; Timothy Kleinig; Helen Brown; Philip Choi; Jiann-Shing Jeng; Annemarei Ranta; Hao-Kuang Wang; Geoffrey C Cloud; Rohan Grimley; Darshan Shah; Neil Spratt; Der-Yang Cho; Karim Mahawish; Lauren Sanders; John Worthington; Ben Clissold; Atte Meretoja; Vignan Yogendrakumar; Mai Duy Ton; Duc Phuc Dang; Nguyen Thai My Phuong; Huy-Thang Nguyen; Chung Y Hsu; Gagan Sharma; Peter J Mitchell; Bernard Yan; Mark W Parsons; Christopher Levi
Journal:  Stroke Vasc Neurol       Date:  2021-11-30
  4 in total

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