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Literature DB >> 34181049

Synergism of Nikkomycin Z in Combination with Diphenyl Diselenide Against Sporothrix spp.

Vanice Rodrigues Poester^1,2, Lívia Silveira Munhoz^1,2, Jéssica Louise Benelli^1,3, Gabriel Baracy Klafke², Cristina Wayne Nogueira⁴, Gilson Rogério Zeni⁴, David A Stevens^5,6, David Larwood^5,7, Melissa Orzechowski Xavier^8,9.

Abstract

We evaluated the in vitro activity of nikkomycin Z (NikZ) in combination with diphenyl diselenide (PhSe)2, two compounds previously shown to have anti-Sporothrix spp. activity. Eighteen isolates of Sporothrix spp. were tested in checkerboard assays. Synergism for inhibition and killing Sporothrix spp. occurred in 100% and 89% of the isolates, respectively. The anti-Sporothrix spp. activity of this combination provides a rationale for in vivo studies to evaluate the application of both compounds in sporotrichosis treatment.

Entities: Chemical Gene

Year: 2021 PMID： 34181049 DOI： 10.1007/s00284-021-02581-y

Source DB: PubMed Journal: Curr Microbiol ISSN： 0343-8651 Impact factor: 2.188

14 in total

1. Changes in biochemical parameters in rabbits blood after oral exposure to diphenyl diselenide for long periods.

Authors: Andreza Fabro de Bem; Rafael de Lima Portella; Juliano Perottoni; Emilene Becker; Denise Bohrer; Márcio Weber Paixão; Cristina Wayne Nogueira; Gilson Zeni; João Batista Teixeira Rocha
Journal: Chem Biol Interact Date: 2006-04-28 Impact factor: 5.192

2. Human sporotrichosis: A zoonotic outbreak in southern Brazil, 2012-2017.

Authors: Tchana Martinez Brandolt; Isabel Martins Madrid; Vanice Rodrigues Poester; Karine Ortiz Sanchotene; Rossana Patricia Basso; Gabriel Baracy Klafke; Márcia de Lima Rodrigues; Melissa Orzechowski Xavier
Journal: Med Mycol Date: 2018-09-28 Impact factor: 4.076

3. Diphenyl diselenide (PhSe)2 inhibits biofilm formation by Candida albicans, increasing both ROS production and membrane permeability.

Authors: Isabela Bueno Rosseti; João Batista Teixeira Rocha; Maricilia Silva Costa
Journal: J Trace Elem Med Biol Date: 2014-08-15 Impact factor: 3.849

Review 4. Global epidemiology of sporotrichosis.

Authors: Arunaloke Chakrabarti; Alexandro Bonifaz; Maria Clara Gutierrez-Galhardo; Takashi Mochizuki; Shanshan Li
Journal: Med Mycol Date: 2014-12-19 Impact factor: 4.076

5. Diphenyl diselenide and its interaction with antifungals against Aspergillus spp.

Authors: Aryse Martins Melo; Vanice Rodrigues Poester; Mariana Trapaga; Cristina Wayne Nogueira; Gilson Zeni; Marife Martinez; Gabriele Sass; David A Stevens; Melissa Orzechowski Xavier
Journal: Med Mycol Date: 2020-08-25 Impact factor: 4.076

6. Low toxicity of diphenyl diselenide in rabbits: a long-term study.

Authors: Andreza Fabro de Bem; Rafael de Lima Portella; Marcelo Farina; Juliano Perottoni; Márcio Weber Paixão; Cristina Wayne Nogueira; João Batista Teixeira Rocha
Journal: Basic Clin Pharmacol Toxicol Date: 2007-07 Impact factor: 4.080

7. 2,2'-Dithienyl diselenide pro-oxidant activity accounts for antibacterial and antifungal activities.

Authors: Ana Paula Pesarico; Gláubia Sartori; Camilla F A dos Santos; José S S Neto; Vandreza Bortolotto; Roberto Christ Vianna Santos; Cristina W Nogueira; Marina Prigol
Journal: Microbiol Res Date: 2013-05-14 Impact factor: 5.415

8. Proteomic analysis of Sporothrix schenckii cell wall reveals proteins involved in oxidative stress response induced by menadione.

Authors: Carlos Félix-Contreras; Carlos A Alba-Fierro; Emmanuel Ríos-Castro; Francisco Luna-Martínez; Mayra Cuéllar-Cruz; Estela Ruiz-Baca
Journal: Microb Pathog Date: 2020-01-19 Impact factor: 3.738

9. Sporotrichosis by Sporothrix schenckii senso stricto with itraconazole resistance and terbinafine sensitivity observed in vitro and in vivo: Case report.

Authors: Rodrigo Vettorato; Daiane Heidrich; Fernanda Fraga; Amanda Carvalho Ribeiro; Danielle Machado Pagani; Carina Timotheo; Tais Guarienti Amaro; Gerson Vettorato; Maria Lúcia Scroferneker
Journal: Med Mycol Case Rep Date: 2017-10-28

Review 10. Zoonotic Epidemic of Sporotrichosis: Cat to Human Transmission.

Authors: Isabella Dib Ferreira Gremião; Luisa Helena Monteiro Miranda; Erica Guerino Reis; Anderson Messias Rodrigues; Sandro Antonio Pereira
Journal: PLoS Pathog Date: 2017-01-19 Impact factor: 6.823

1 in total

1. Treatment of Human Sporotrichosis Caused by Sporothrix brasiliensis.

Authors: Vanice Rodrigues Poester; Rossana Patricia Basso; David A Stevens; Lívia Silveira Munhoz; Vanessa Brito de Souza Rabello; Rodrigo Almeida-Paes; Rosely Maria Zancopé-Oliveira; Mariza Zanchi; Jéssica Louise Benelli; Melissa Orzechowski Xavier
Journal: J Fungi (Basel) Date: 2022-01-10

1 in total