Literature DB >> 34175852

Geriatric Patients and Symptomatic Urinary Tract Infections: Analysis of Bacterial Range and Resistance Rates at a 3rd Level of Care Hospital in Germany.

Ann-Sera Manseck1, Wolfgang Otto1,2,3, Marco Schnabel1, Stefan Denzinger1, Maximilian Burger1, Philipp Julian Spachmann1.   

Abstract

BACKGROUND: Increasing life expectancy and demographic change result in a rising number of geriatric patients, but knowledge about geriatric treatment options and adapted diagnostic pathways is low. Simultaneously, urinary tract infections (UTIs) are common in older people and often difficult to treat.
METHODS: Patients with a UTI at a urological outpatient department between January 01, 2016, and December 31, 2017, were retrospectively identified in the data system. One thousand one hundred fifteen patients with "N30" and "N39" diagnosis were included in this study, 965 of which were under the age of 75 (group 1) and 150 of which 75 years or older (group 2).
RESULTS: Of 150 patients in group 2, 41.6% had nitrite-positive urine (vs. 20.9% in group 1, p < 0.05 in χ2 testing). Patients in group 2 often had indwelling devices (30.3 vs. 6.0%, p < 0.05) and presented a sterile urine culture in only 20.7% (vs. 40.1% in group 1). Regarding calculated antibiotic therapy, there were significant differences concerning prescription of ciprofloxacin (34.9 vs. 25%, p < 0.05) and fosfomycin (12.7 vs. 40.7%, p < 0.05).
CONCLUSION: UTI in geriatric patients should be treated differently than in younger patients because antibiotic resistance is high. The group with indwelling devices is complex. Individual strategies for geriatric patients should be considered.
© 2021 The Author(s). Published by S. Karger AG, Basel.

Entities:  

Keywords:  Antibiotic stewardship; Antimicrobial resistance rates; Calculated antibiotic therapy; Community-acquired urinary tract infection; Elderly patients; Geriatric patients; Infection; Symptomatic urinary tract infection; Urinary tract infection

Mesh:

Substances:

Year:  2021        PMID: 34175852      PMCID: PMC8985023          DOI: 10.1159/000516677

Source DB:  PubMed          Journal:  Urol Int        ISSN: 0042-1138            Impact factor:   2.089


  16 in total

Review 1.  Epidemiology and unique aspects of aging and infectious diseases.

Authors:  T T Yoshikawa
Journal:  Clin Infect Dis       Date:  2000-06-30       Impact factor: 9.079

2.  Urinary tract infection in old age: over-diagnosed and over-treated.

Authors:  M E McMurdo; N D Gillespie
Journal:  Age Ageing       Date:  2000-07       Impact factor: 10.668

3.  [Nosocomial urinary tract infections in the geriatric hospital - pathogen spectrum and resistancies].

Authors:  R Thiesemann; E-U Walter; I Füsgen
Journal:  Z Gerontol Geriatr       Date:  2008-03-11       Impact factor: 1.281

Review 4.  [Urinary tract infections in the elderly].

Authors:  N Mirsaidov; F M E Wagenlehner
Journal:  Urologe A       Date:  2016-04       Impact factor: 0.639

5.  Infectious disease hospitalizations among older adults in the United States from 1990 through 2002.

Authors:  Aaron T Curns; Robert C Holman; James J Sejvar; Maria F Owings; Lawrence B Schonberger
Journal:  Arch Intern Med       Date:  2005-11-28

6.  Predictors of urinary tract infection after menopause: a prospective study.

Authors:  Sara L Jackson; Edward J Boyko; Delia Scholes; Linn Abraham; Kalpana Gupta; Stephan D Fihn
Journal:  Am J Med       Date:  2004-12-15       Impact factor: 4.965

Review 7.  Epidemiology of urinary tract infections: incidence, morbidity, and economic costs.

Authors:  Betsy Foxman
Journal:  Am J Med       Date:  2002-07-08       Impact factor: 4.965

8.  Diagnostic accuracy of criteria for urinary tract infection in a cohort of nursing home residents.

Authors:  Manisha Juthani-Mehta; Mary Tinetti; Eleanor Perrelli; Virginia Towle; Peter H Van Ness; Vincent Quagliarello
Journal:  J Am Geriatr Soc       Date:  2007-07       Impact factor: 5.562

9.  Urinary Tract Infection in Elderly: Clinical Profile and Outcome.

Authors:  Pranit Kakde; Neelam N Redkar; Abhijeet Yelale
Journal:  J Assoc Physicians India       Date:  2018-06

10.  The association between indwelling urinary catheter use in the elderly and urinary tract infection in acute care.

Authors:  Susan E Hazelett; Margaret Tsai; Michele Gareri; Kyle Allen
Journal:  BMC Geriatr       Date:  2006-10-12       Impact factor: 3.921

View more
  2 in total

1.  Cranberry Supplement, D-Mannose, and Other OTC Modalities for Prevention of Recurrent UTI in Women Post-Electrofulguration.

Authors:  Parker R M Kenee; Alana L Christie; Philippe E Zimmern
Journal:  Int J Womens Health       Date:  2022-05-03

2.  Efficacy of Fosfomycin against Planktonic and Biofilm-Associated MDR Uropathogenic Escherichia coli Clinical Isolates.

Authors:  Haziel Eleazar Dzib-Baak; Andrés Humberto Uc-Cachón; Angel de Jesús Dzul-Beh; Rey Fernando Rosado-Manzano; Carlos Gracida-Osorno; Gloria María Molina-Salinas
Journal:  Trop Med Infect Dis       Date:  2022-09-08
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.