Katiúscia Gomes Nunes1,2,3,4, Neusa Sica da Rocha5,6,7. 1. Graduation Program in Psychiatry and Behavior Science, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil. k.gomes.nunes@gmail.com. 2. Center of Clinical Research, Center of Experimental Research, and Psychiatric Service Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil. k.gomes.nunes@gmail.com. 3. I-QOL: Innovations and Interventions for Quality of Life Research Group, Porto Alegre, Brazil. k.gomes.nunes@gmail.com. 4. , Porto Alegre, Brazil. k.gomes.nunes@gmail.com. 5. Graduation Program in Psychiatry and Behavior Science, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil. 6. Center of Clinical Research, Center of Experimental Research, and Psychiatric Service Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil. 7. I-QOL: Innovations and Interventions for Quality of Life Research Group, Porto Alegre, Brazil.
Abstract
PURPOSE: To evaluate resilience in severe mental disorders and correlate it with clinical measures and quality of life. METHODS: Resilience (Resilience Scale, RS) and quality of life (WHOQOL-BREF questionnaire) were prospectively evaluated in a sample of 384 hospitalized patients diagnosed with severe mental disorders (depression, bipolar disorder and schizophrenia). Clinical outcomes were measured using the Global Assessment of Functioning Scale (GAF), Clinical Global Impression (CGI), Cumulative Illness Rating Scale (CIRS), Hamilton Scale-Depression (HAM-D), Young Mania Rating Scale (YMRS), and Brief Psychiatric Rating Scale (BPRS). RESULTS: Resilience measure showed a difference between the three clinical groups analyzed in the study, with lower scores in depressed patients than in bipolar disorder or schizophrenia patients. There was a trend toward a correlation between resilience and depressive symptoms (Hamilton Scale-Depression; P = 0.052; rs = - 0.163). The scores in the resilience scale's personal competence domain presented a tendency of association with general psychiatric symptoms (Brief Psychiatric Rating Scale; P = 0.058; r = - 0.138). There was a significantly positive association between resilience and all domains of quality of life (r = 0.306-0.545; P < 0.05). Sociodemographic data like age, education, intelligence quotient, sex, and marital status were associated with resilience. CONCLUSION: Depressive patients had low scores on the resilience scale compared to patients with other disorders. Resilience was positively associated with quality of life. Therefore, it deserves special attention, as it promotes more positive outcomes and improves patients' quality of life with severe mental disorders.
PURPOSE: To evaluate resilience in severe mental disorders and correlate it with clinical measures and quality of life. METHODS: Resilience (Resilience Scale, RS) and quality of life (WHOQOL-BREF questionnaire) were prospectively evaluated in a sample of 384 hospitalized patients diagnosed with severe mental disorders (depression, bipolar disorder and schizophrenia). Clinical outcomes were measured using the Global Assessment of Functioning Scale (GAF), Clinical Global Impression (CGI), Cumulative Illness Rating Scale (CIRS), Hamilton Scale-Depression (HAM-D), Young Mania Rating Scale (YMRS), and Brief Psychiatric Rating Scale (BPRS). RESULTS: Resilience measure showed a difference between the three clinical groups analyzed in the study, with lower scores in depressed patients than in bipolar disorder or schizophrenia patients. There was a trend toward a correlation between resilience and depressive symptoms (Hamilton Scale-Depression; P = 0.052; rs = - 0.163). The scores in the resilience scale's personal competence domain presented a tendency of association with general psychiatric symptoms (Brief Psychiatric Rating Scale; P = 0.058; r = - 0.138). There was a significantly positive association between resilience and all domains of quality of life (r = 0.306-0.545; P < 0.05). Sociodemographic data like age, education, intelligence quotient, sex, and marital status were associated with resilience. CONCLUSION: Depressive patients had low scores on the resilience scale compared to patients with other disorders. Resilience was positively associated with quality of life. Therefore, it deserves special attention, as it promotes more positive outcomes and improves patients' quality of life with severe mental disorders.
Authors: Toni-Kim Clarke; Yanni Zeng; Lauren Navrady; Charley Xia; Chris Haley; Archie Campbell; Pau Navarro; Carmen Amador; Mark J Adams; David M Howard; Aleix Soler; Caroline Hayward; Pippa A Thomson; Blair H Smith; Sandosh Padmanabhan; Lynne J Hocking; Lynsey S Hall; David J Porteous; Ian J Deary; Andrew M McIntosh Journal: Wellcome Open Res Date: 2019-01-14