| Literature DB >> 34173108 |
O V Zemchenkova1, O V Basharina2, V G Artyukhov2.
Abstract
The effect of UV-light (240-390 nm) in doses of 151 and 755 J/m2 on the expression of membrane markers CD5, CD19, CD20 in human peripheral blood B cells was studied by flow cytometry. In 24 h after exposure to UV light, we observed activation of processes accompanied by structural rearrangements of B-cell membranes leading to changes in the expression of receptor molecules: the content of of CD19 and CD20 increased due to activation of the synthesis of these proteins, while the content of CD5 decreased. The percentage of CD5+ cells decreased over 24 h after UV-irradiation of lymphocytes, while addition of autologous plasma to the incubation medium produced a photoprotective effect on CD5+ cells.Entities:
Keywords: B cells; UV irradiation; membrane markers CD5, CD19, CD20
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Year: 2021 PMID: 34173108 DOI: 10.1007/s10517-021-05214-3
Source DB: PubMed Journal: Bull Exp Biol Med ISSN: 0007-4888 Impact factor: 0.804