Comparison of fructosamine and glycated haemoglobin in children with type 1 (insulin-dependent) diabetes mellitus.

In six children (age: mean 8.4 years, range 2.2-12.6 years) with newly diagnosed Type 1 (insulin-dependent) diabetes mellitus, plasma fructosamine and glycated haemoglobin (HbA1) were compared in respect to their disappearance during the first month after diagnosis during well controlled glycaemia. The disappearance of the surplus plasma fructosamine and HbA1 was calculated applying exponential equations. The estimated half-lives of fructosamine (mean 57.2 days, range 40.7-77 days) and HbA1 (mean 59.7 days, range 43.3-82 days) were not significantly different, a finding which is left unexplained.