| Literature DB >> 34169944 |
Yiren Cao1, Jinjun Wu1, Bo Pang1, Hongquan Zhang1, X Chris Le1.
Abstract
The trans-cleavage activity of the target-activated CRISPR/Cas12a liberated an RNA crosslinker from a molecular transducer, which facilitated the assembly of gold nanoparticles. Integration of the molecular transducer with isothermal amplification and CRISPR/Cas12a resulted in visual detection of the N gene and E gene of SARS-CoV-2 in 45 min.Entities:
Year: 2021 PMID: 34169944 DOI: 10.1039/d1cc02546e
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222