Koech Irene1, Poli Philippe Amubuomombe2,3, Richard Mogeni1, Cheruiyot Andrew4, Ann Mwangi5, Orang'o Elkanah Omenge1,4. 1. Reproductive Health, Moi Teaching& Referral Hospital, PO Box 3-30100, Nandi road, Eldoret, Kenya. 2. Reproductive Health, Moi Teaching& Referral Hospital, PO Box 3-30100, Nandi road, Eldoret, Kenya. philippe_poli@yahoo.fr. 3. Department of Reproductive Health, Moi University School of Medicine, P. O. Box 4606-30100, Eldoret, Kenya. philippe_poli@yahoo.fr. 4. Department of Reproductive Health, Moi University School of Medicine, P. O. Box 4606-30100, Eldoret, Kenya. 5. Department of Behavioural Sciences, Moi University School of Medicine, P.O. Box 4606-30100, Eldoret, Kenya.
Abstract
BACKGROUND: Eclampsia, considered as serious complication of preeclampsia, remains a life-threatening condition among pregnant women. It accounts for 12% of maternal deaths and 16-31% of perinatal deaths worldwide. Most deaths from eclampsia occurred in resource-limited settings of sub-Saharan Africa. This study was performed to determine the optimum mode of delivery, as well as factors associated with the mode of delivery, in women admitted with eclampsia at Riley Mother and Baby Hospital. METHODS: This was a hospital-based longitudinal case-series study conducted at the largest and busiest obstetric unit of the tertiary hospital of western Kenya. Maternal and perinatal variables, such as age, parity, medications, initiation of labour, mode of delivery, admission to the intensive care unit, admission to the newborn care unit, organ injuries, and mortality, were analysed using the Statistical Package for the Social Sciences software version 20.0. Quantitative data were described using frequencies and percentages. The significance of the obtained results was judged at the 5% level. The chi-square test was used for categorical variables, and Fisher's exact test or the Monte Carlo correction was used for correction of the chi-square test when more than 20% of the cells had an expected count of less than 5. RESULTS: During the study period, 53 patients diagnosed with eclampsia were treated and followed up to 6 weeks postpartum. There was zero maternal mortality; however, perinatal mortality was reported in 9.4%. Parity was statistically associated with an increased odds of adverse perinatal outcomes (p = 0.004, OR = 9.1, 95% CI = 2.0-40.8) and caesarean delivery (p = 0.020, OR = 4.7, 95% CI = 1.3-17.1). In addition, the induction of labour decreased the risk of adverse outcomes (p = 0.232, OR = 0.3, 95% CI = 0.1-2.0). CONCLUSION: There is no benefit of emergency caesarean section for women with eclampsia. This study showed that induction of labour and vaginal delivery can be successfully achieved in pregnant women with eclampsia. Maternal and perinatal mortality from eclampsia can be prevented through prompt and effective care.
BACKGROUND:Eclampsia, considered as serious complication of preeclampsia, remains a life-threatening condition among pregnant women. It accounts for 12% of maternal deaths and 16-31% of perinatal deaths worldwide. Most deaths from eclampsia occurred in resource-limited settings of sub-Saharan Africa. This study was performed to determine the optimum mode of delivery, as well as factors associated with the mode of delivery, in women admitted with eclampsia at Riley Mother and Baby Hospital. METHODS: This was a hospital-based longitudinal case-series study conducted at the largest and busiest obstetric unit of the tertiary hospital of western Kenya. Maternal and perinatal variables, such as age, parity, medications, initiation of labour, mode of delivery, admission to the intensive care unit, admission to the newborn care unit, organ injuries, and mortality, were analysed using the Statistical Package for the Social Sciences software version 20.0. Quantitative data were described using frequencies and percentages. The significance of the obtained results was judged at the 5% level. The chi-square test was used for categorical variables, and Fisher's exact test or the Monte Carlo correction was used for correction of the chi-square test when more than 20% of the cells had an expected count of less than 5. RESULTS: During the study period, 53 patients diagnosed with eclampsia were treated and followed up to 6 weeks postpartum. There was zero maternal mortality; however, perinatal mortality was reported in 9.4%. Parity was statistically associated with an increased odds of adverse perinatal outcomes (p = 0.004, OR = 9.1, 95% CI = 2.0-40.8) and caesarean delivery (p = 0.020, OR = 4.7, 95% CI = 1.3-17.1). In addition, the induction of labour decreased the risk of adverse outcomes (p = 0.232, OR = 0.3, 95% CI = 0.1-2.0). CONCLUSION: There is no benefit of emergency caesarean section for women with eclampsia. This study showed that induction of labour and vaginal delivery can be successfully achieved in pregnant women with eclampsia. Maternal and perinatal mortality from eclampsia can be prevented through prompt and effective care.
Entities:
Keywords:
Eclampsia; Maternal and perinatal outcomes; Mode of delivery; Resource-limited settings
Authors: Alfred Kwesi Manyeh; Alberta Amu; David Etsey Akpakli; John Williams; Margaret Gyapong Journal: BMC Pregnancy Childbirth Date: 2018-10-16 Impact factor: 3.007
Authors: Ana Filipa Silva; José Afonso; António Sampaio; Nuno Pimenta; Ricardo Franco Lima; Henrique de Oliveira Castro; Rodrigo Ramirez-Campillo; Israel Teoldo; Hugo Sarmento; Francisco González Fernández; Agnieszka Kaczmarek; Anna Oniszczuk; Eugenia Murawska-Ciałowicz Journal: Front Psychol Date: 2022-09-22