Literature DB >> 3416611

Integrity of semantic fields in Alzheimer's disease.

R D Nebes1, C B Brady.   

Abstract

It has been suggested that Alzheimer patients retain general semantic knowledge about concrete objects (e.g., category membership) but lose information about objects' distinctive features and functions. To test this hypothesis, normal young and old subjects and Alzheimer patients were given a concrete concept. They were then shown a series of words and for each had to say whether it was related to the concept. Of the words that were related to a given concept, one was a physical feature, another a function, another the object's superordinate category, and another a generally associated concept. In comparison to the normals, Alzheimer patients were not disproportionately worse at making decisions about features and actions than they were about categories and general associates. Also, while Alzheimer patients were less accurate in generating features, actions and associates to a given concept than were normals, they were not differentially more impaired on any one type.

Entities:  

Mesh:

Year:  1988        PMID: 3416611     DOI: 10.1016/s0010-9452(88)80037-6

Source DB:  PubMed          Journal:  Cortex        ISSN: 0010-9452            Impact factor:   4.027


  4 in total

Review 1.  Changes in cognition.

Authors:  Marilyn S Albert
Journal:  Neurobiol Aging       Date:  2011-12       Impact factor: 4.673

2.  Verbal fluency performance in amnestic MCI and older adults with cognitive complaints.

Authors:  Katherine E Nutter-Upham; Andrew J Saykin; Laura A Rabin; Robert M Roth; Heather A Wishart; Nadia Pare; Laura A Flashman
Journal:  Arch Clin Neuropsychol       Date:  2008-03-12       Impact factor: 2.813

3.  Categorization of object descriptions in Alzheimer's disease and frontotemporal dementia: limitation in rule-based processing.

Authors:  Murray Grossman; Edward E Smith; Phyllis L Koenig; Guila Glosser; Jina Rhee; Kari Dennis
Journal:  Cogn Affect Behav Neurosci       Date:  2003-06       Impact factor: 3.282

4.  The underlying mechanisms of semantic memory loss in Alzheimer's disease and semantic dementia.

Authors:  Sean L Rogers; Rhonda B Friedman
Journal:  Neuropsychologia       Date:  2007-08-22       Impact factor: 3.139

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.