Zeyi Cheng1, Luchen Wang2, Xiaogang Sun2. 1. Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, China. 2. Aortic and Vascular Surgery Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
We have read with great interest the article titled “Overweight is associated with better one-year survival in elderly patients after cardiac surgery: a retrospective analysis of the MIMIC-III database.” by Zhang (1). The article pointed that overweight was associated with better 1-year survival in patients after cardiac surgery when compared to normal weight. The protective effect of overweight on post-cardiac surgery survival was confined to elderly patients (>60 years).We have some comments on this conclusion. First, the authors collected BMI, age, gender, smoking, drinking, and other parameters for analysis, but they didn’t explain the height and weight, only BMI could not reach such a conclusion, Ranucci et al. conducted a retrospective cohort study included 7,939 consecutive patients who underwent cardiac surgery, they find contrary to men, in women obesity does not reduce the operative mortality in cardiac surgery, whereas the height seems to be associated with a lower mortality (2). Next, the results were derived from multiple centers, postoperative management strategies may also affect the follow-up outcomes, such as oral anticoagulant, embolism events, bleeding events, which constituted confounding bias to reach such a conclusion. What’s more, propensity matching cannot account for clustering after matching and other clinical factors in the perioperative period that could have impacted outcomes in these patients. Finally, the authors didn’t introduce the atrial fibrillation (AF) history, as we all known, AF occurrence is more common after cardiac surgery, Serban et al. (3) pointed out that obesity predisposes to a larger number of prolonged AF episodes in the early postoperative period after cardiac surgery for CAD or valvular heart disease. Phan et al. (4) made a meta-analysis and suggested that obesity is associated with a moderately higher risk of Post-operative AF (POAF), While POAF is also related to an increased incidence of stroke, 30-day mortality and respiratory complications. So we believe it is better to add those parameters to come to a more convincing conclusion.The article’s supplementary files as
Authors: Corina Serban; Johnmary T Arinze; Roeliene Starreveld; Eva A H Lanters; Ameeta Yaksh; Charles Kik; Yalin Acardag; Paul Knops; Ad J J C Bogers; Natasja M S de Groot Journal: J Thorac Cardiovasc Surg Date: 2019-04-04 Impact factor: 5.209
Authors: Marco Ranucci; Carlo de Vincentiis; Lorenzo Menicanti; Maria Teresa La Rovere; Valeria Pistuddi Journal: Eur J Cardiothorac Surg Date: 2019-07-01 Impact factor: 4.191