Literature DB >> 34163062

Targeting calcium-related mechanotransduction in early OA.

Michelle L Delco1, Lawrence J Bonassar2,3.   

Abstract

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Year:  2021        PMID： 34163062     DOI： 10.1038/s41584-021-00649-4

Source DB:  PubMed          Journal:  Nat Rev Rheumatol        ISSN： 1759-4790            Impact factor:   32.286


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  1 in total

1.  A dysfunctional TRPV4-GSK3β pathway prevents osteoarthritic chondrocytes from sensing changes in extracellular matrix viscoelasticity.

Authors:  Pranay Agarwal; Hong-Pyo Lee; Piera Smeriglio; Fiorella Grandi; Stuart Goodman; Ovijit Chaudhuri; Nidhi Bhutani
Journal:  Nat Biomed Eng       Date:  2021-03-11       Impact factor: 29.234
  1 in total
  5 in total

Review 1.  Mechanosignalling in cartilage: an emerging target for the treatment of osteoarthritis.

Authors:  Tom Hodgkinson; Domhnall C Kelly; Caroline M Curtin; Fergal J O'Brien
Journal:  Nat Rev Rheumatol       Date:  2021-12-21       Impact factor: 20.543

Review 2.  The Role of Mechanically-Activated Ion Channels Piezo1, Piezo2, and TRPV4 in Chondrocyte Mechanotransduction and Mechano-Therapeutics for Osteoarthritis.

Authors:  Winni Gao; Hamza Hasan; Devon E Anderson; Whasil Lee
Journal:  Front Cell Dev Biol       Date:  2022-05-04

3.  A molecular map of long non-coding RNA expression, isoform switching and alternative splicing in osteoarthritis.

Authors:  Georgia Katsoula; Julia Steinberg; Margo Tuerlings; Rodrigo Coutinho de Almeida; Lorraine Southam; Diane Swift; Ingrid Meulenbelt; J Mark Wilkinson; Eleftheria Zeggini
Journal:  Hum Mol Genet       Date:  2022-06-22       Impact factor: 5.121

4.  A Novel Pro-Inflammatory Mechanosensing Pathway Orchestrated by the Disintegrin Metalloproteinase ADAM15 in Synovial Fibroblasts.

Authors:  Tomasz Janczi; Florian Meier; Yuliya Fehrl; Raimund W Kinne; Beate Böhm; Harald Burkhardt
Journal:  Cells       Date:  2021-10-09       Impact factor: 6.600

Review 5.  TRPV4 and PIEZO Channels Mediate the Mechanosensing of Chondrocytes to the Biomechanical Microenvironment.

Authors:  Min Zhang; Nan Meng; Xiaoxiao Wang; Weiyi Chen; Quanyou Zhang
Journal:  Membranes (Basel)       Date:  2022-02-18
  5 in total

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