| Literature DB >> 34161260 |
Katherine R Amato1, Marie-Claire Arrieta2,3, Meghan B Azad4,5, Michael T Bailey6,7, Josiane L Broussard8, Carlijn E Bruggeling9, Erika C Claud10, Elizabeth K Costello11, Emily R Davenport12, Bas E Dutilh13,14, Holly A Swain Ewald15, Paul Ewald15, Erin C Hanlon16, Wrenetha Julion17, Ali Keshavarzian18, Corinne F Maurice19, Gregory E Miller20,21, Geoffrey A Preidis22, Laure Segurel23, Burton Singer24, Sathish Subramanian25,26, Liping Zhao27,28, Christopher W Kuzawa29,21.
Abstract
Individuals who are minoritized as a result of race, sexual identity, gender, or socioeconomic status experience a higher prevalence of many diseases. Understanding the biological processes that cause and maintain these socially driven health inequities is essential for addressing them. The gut microbiome is strongly shaped by host environments and affects host metabolic, immune, and neuroendocrine functions, making it an important pathway by which differences in experiences caused by social, political, and economic forces could contribute to health inequities. Nevertheless, few studies have directly integrated the gut microbiome into investigations of health inequities. Here, we argue that accounting for host-gut microbe interactions will improve understanding and management of health inequities, and that health policy must begin to consider the microbiome as an important pathway linking environments to population health.Entities:
Keywords: DOHad; chronic disease; health disparities; policy; structural racism
Mesh：
Year: 2021 PMID： 34161260 PMCID： PMC8237592 DOI： 10.1073/pnas.2017947118
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205