Literature DB >> 3416074

DDAVP and epinephrine-induced changes in the localization of von Willebrand factor antigen in endothelial cells of human oral mucosa.

M Takeuchi1, H Nagura, T Kaneda.   

Abstract

A peroxidase-labeled antibody technique revealed von Willebrand factor antigen (vWF:Ag) in rough endoplasmic reticulum (rER), the perinuclear region, and the cytoplasmic vesicles of capillary endothelial cells in oral mucosa. After administration of epinephrine or 1-deamino-8-D-arginine vasopressin (DDAVP), the localization of vWF:Ag was shown to have changed to the basement membrane and the surrounding interstitium. This change of vWF:Ag localization induced by epinephrine and DDAVP may play a role in the adhesion of platelets to subendothelium following endothelial injury during surgery and may be an unknown hemostatic effect of these drugs.

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Year:  1988        PMID： 3416074

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  8 in total

1.  Differing microvasculature in the two major types of gastric carcinoma: a conventional, ultrastructural and ultrastructural immunolocalization study of von Willebrand factor.

Authors:  H Ohtani; H Nagura
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1990

2.  The diagnosis and treatment of von Willebrand disease in children.

Authors:  Robert J Klaassen; Jacqueline M Halton
Journal:  Paediatr Child Health       Date:  2002-04       Impact factor: 2.253

3.  Phenotypic heterogeneity of vascular endothelial cells in the human kidney.

Authors:  T Kinjo; M Takashi; K Miyake; H Nagura
Journal:  Cell Tissue Res       Date:  1989-04       Impact factor: 5.249

4.  A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11.

Authors:  K L Mohlke; W C Nichols; R J Westrick; E K Novak; K A Cooney; R T Swank; D Ginsburg
Journal:  Proc Natl Acad Sci U S A       Date:  1996-12-24       Impact factor: 11.205

5.  Intracellular trafficking of factor VIII to von Willebrand factor storage granules.

Authors:  J B Rosenberg; P A Foster; R J Kaufman; E A Vokac; M Moussalli; P A Kroner; R R Montgomery
Journal:  J Clin Invest       Date:  1998-02-01       Impact factor: 14.808

6.  Light and electron microscopic immunolocalization of endothelial leucocyte adhesion molecule-1 in inflammatory bowel disease. Morphological evidence of active synthesis and secretion into vascular lumen.

Authors:  H Ohtani; S Nakamura; Y Watanabe; K Fukushima; T Mizoi; M Kimura; N Hiwatashi; H Nagura
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1992

7.  Phenotypic characterization of alveolar capillary endothelial cells, alveolar epithelial cells and alveolar macrophages in patients with pulmonary fibrosis, with special reference to MHC class II antigens.

Authors:  T Komatsu; M Yamamoto; K Shimokata; H Nagura
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1989

8.  Desmopressin acetate use in von Willebrand's disease: a survey on current practices in Brazil.

Authors:  Maria Sueli da Silva Namen Lopes; Suely Meireles Rezende
Journal:  Hematol Transfus Cell Ther       Date:  2020-01-30
  8 in total

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