Literature DB >> 3415941

Cobalt plaque versus enucleation for uveal melanoma: comparison of survival rates.

K S Adams1, D H Abramson, R M Ellsworth, B G Haik, M Bedford, S Packer, J Seddon, D Albert, L Polivogianis.   

Abstract

Two hundred and twenty-three patients treated by cobalt plaque for uveal melanoma were compared with 416 patients treated by enucleation for uveal melanoma in terms of patient survival. The median follow-up time for the patients treated by cobalt plaque was 4.3 years. Kaplan-Meier survival curves were calculated up to five years following treatment based on time to tumour-related deaths. Cox's proportional hazards multivariate analysis was performed to determine which variables were related to melanoma-related deaths while controlling for age, size, and location of the tumours. Statistically significant predictive factors were location of tumour and largest tumour dimension. There was not a statistically significant difference in survival between patients treated by cobalt plaque and those treated by enucleation.

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Year:  1988        PMID: 3415941      PMCID: PMC1041512          DOI: 10.1136/bjo.72.7.494

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  7 in total

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7.  A prognostic factor study of disease-free interval and survival following enucleation for uveal melanoma.

Authors:  J M Seddon; D M Albert; P T Lavin; N Robinson
Journal:  Arch Ophthalmol       Date:  1983-12
  7 in total
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