BACKGROUND: The senses serve as the crucial interface between the individual and the environment. They are subject to aging and disease processes. METHODS: This review is based on pertinent publications retrieved by a selective search in the Medline and Cochrane Library databases. RESULTS: Approximately 40% of persons aged 70 to 79 manifest dysfunction in at least one, and more than 25% in multiple senses. Sensory changes are accompanied by diverse comorbidities which depend on the particular sense(s) affected. The presence of sensory deficits is associated with an increased risk of developing dementia (OR: 1.49 [95% confidence interval: 1.12; 1.98] for dysfunction in a single sensory modality, 2.85 [1.88; 4.30] for dysfunction in three or more sensory modalities). The risk of developing depressive symptoms is elevated as well (OR 3.36 [2.28; 4.96]). The individual's ability to cope with the demands of everyday life is largely determined by the ability to carry out multisensory integration, in which the perceptions of the different senses are bound together. This function itself is subject to age-related changes that can be either adaptive or maladaptive; it can, therefore, serve as an indicator for pathological aging processes. CONCLUSION: Sensory dysfunction in old age should be detected as early as possible. This implies the need for close collaboration of all of the involved disciplines. It would be desirable to develop sensory screening tests as well as a procedure for testing multisensory integration in routine clinical practice.
BACKGROUND: The senses serve as the crucial interface between the individual and the environment. They are subject to aging and disease processes. METHODS: This review is based on pertinent publications retrieved by a selective search in the Medline and Cochrane Library databases. RESULTS: Approximately 40% of persons aged 70 to 79 manifest dysfunction in at least one, and more than 25% in multiple senses. Sensory changes are accompanied by diverse comorbidities which depend on the particular sense(s) affected. The presence of sensory deficits is associated with an increased risk of developing dementia (OR: 1.49 [95% confidence interval: 1.12; 1.98] for dysfunction in a single sensory modality, 2.85 [1.88; 4.30] for dysfunction in three or more sensory modalities). The risk of developing depressive symptoms is elevated as well (OR 3.36 [2.28; 4.96]). The individual's ability to cope with the demands of everyday life is largely determined by the ability to carry out multisensory integration, in which the perceptions of the different senses are bound together. This function itself is subject to age-related changes that can be either adaptive or maladaptive; it can, therefore, serve as an indicator for pathological aging processes. CONCLUSION:Sensory dysfunction in old age should be detected as early as possible. This implies the need for close collaboration of all of the involved disciplines. It would be desirable to develop sensory screening tests as well as a procedure for testing multisensory integration in routine clinical practice.
Authors: Christiane Völter; Lisa Götze; Marcel Bajewski; Stefan Dazert; Jan Peter Thomas Journal: Front Aging Neurosci Date: 2022-03-21 Impact factor: 5.750
Authors: Elke Warmerdam; Maike Schumacher; Thorben Beyer; Patrik Theodor Nerdal; Linda Schebesta; Klarissa H Stürner; Kirsten E Zeuner; Clint Hansen; Walter Maetzler Journal: Front Neurol Date: 2022-03-29 Impact factor: 4.003