Literature DB >> 34157817

Evaluation of Prescribing Patterns of Antibiotics Using Selected Indicators for Antimicrobial Use in Hospitals and the Access, Watch, Reserve (AWaRe) Classification by the World Health Organization

Vinodkumar Mugada1, Varsha Mahato1, Damayanthi Andhavaram1, Sairam Mouli Vajhala1.   

Abstract

Objectives: Antibiotic resistance poses a significant threat to the world, and irrational use of antibiotics is a major contributing factor. Evaluation of antimicrobial use is underway with the help of indicators and the World Health Organization (WHO) classification of antibiotics into Access, Watch, and Reserve (AWaRe) categories. We aimed to evaluate the prescribing pattern of antibiotics using the AWaRe classification by the WHO and selected indicators for antimicrobial use in hospitals. Materials and
Methods: A total of 1.000 prescriptions were analyzed during the study for antibiotic prescribing patterns. Antibiotic consumption was calculated using defined daily dose (DDD) methodology. The prescribing pattern was evaluated using the WHO classification of antibiotics into the categories AWaRe and using selected indicators (hospital and prescribing) for antimicrobial use in hospitals.
Results: A total of 1.128 antibiotics were prescribed during the study. The 19-44 age group was prescribed a high number of antibiotics (n=510). Females were prescribed a high number of antibiotics compared with males (n=602). Azithromycin was the most commonly consumed antibiotic (14.97 DDD/1000/day). Four antibiotics from the Access category and five from the Watch category were prescribed in the study. The Watch category of antibiotics were consumed in a high number. There were no standard treatment guidelines in the hospital. In all, 98.0% of antibiotics were consistent with the hospital formulary and prescribed under generic names. The average number of antibiotics prescribed per patient was 1.12. The average duration of antimicrobial treatment was 5.24 days. The percentage of patients prescribed antimicrobials for pneumonia in accordance with treatment guidelines was 13.28%.
Conclusion: Irrational use of antibiotics exists in hospitals. There is a need to maintain standard treatment guidelines in the hospital because it prevents irrational use of antibiotics.

Entities:  

Keywords:  Access; Reserve; WHO; Watch; antibiotic; evaluation; hospital; indicator; prescribing

Year:  2021        PMID: 34157817      PMCID: PMC8231325          DOI: 10.4274/tjps.galenos.2020.11456

Source DB:  PubMed          Journal:  Turk J Pharm Sci        ISSN: 1304-530X


  17 in total

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Authors:  David Baur; Beryl Primrose Gladstone; Francesco Burkert; Elena Carrara; Federico Foschi; Stefanie Döbele; Evelina Tacconelli
Journal:  Lancet Infect Dis       Date:  2017-06-16       Impact factor: 25.071

2.  Antimicrobial prescribing patterns of surgical speciality in a tertiary care hospital in India: Role of persuasive intervention for changing antibiotic prescription behaviour.

Authors:  Chand Wattal; Shilpi Khanna; Neeraj Goel; Jaswinder Kaur Oberoi; B K Rao
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3.  Classifying antibiotics in the WHO Essential Medicines List for optimal use-be AWaRe.

Authors:  Mike Sharland; Celine Pulcini; Stephan Harbarth; Mei Zeng; Sumanth Gandra; Shrey Mathur; Nicola Magrini
Journal:  Lancet Infect Dis       Date:  2017-12-20       Impact factor: 25.071

4.  WHO/INRUD prescribing indicators and prescribing trends of antibiotics in the Accident and Emergency Department of Bahawal Victoria Hospital, Pakistan.

Authors:  Muhammad Atif; Muhammad Azeem; Muhammad Rehan Sarwar; Samia Shahid; Sidra Javaid; Huria Ikram; Uzma Baig; Shane Scahill
Journal:  Springerplus       Date:  2016-11-08

Review 5.  Antibiotic resistance in the wild: an eco-evolutionary perspective.

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Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2017-01-19       Impact factor: 6.237

6.  Antibiotic Utilization in Pediatric Hospitalized Patients - A Single Center Study.

Authors:  Hasime Qorraj Bytyqi; Rexhep Hoxha; Elton Bahtiri; Valon Krasniqi; Shaip Krasniqi
Journal:  Open Access Maced J Med Sci       Date:  2017-03-24

7.  Investigation of antimicrobial use at a tertiary care hospital in Southern Punjab, Pakistan using WHO methodology.

Authors:  Muhammad Atif; Muhammad Azeem; Anum Saqib; Shane Scahill
Journal:  Antimicrob Resist Infect Control       Date:  2017-04-28       Impact factor: 4.887

8.  The Evaluation of Antibiotic Consumption at the Inpatient Level in Kazakhstan from 2011 to 2018.

Authors:  Gulzira Zhussupova; Galina Skvirskaya; Vladimir Reshetnikov; Viktorija Dragojevic-Simic; Nemanja Rancic; Dinara Utepova; Mihajlo Jakovljevic
Journal:  Antibiotics (Basel)       Date:  2020-02-02

9.  Measurement of adult antimicrobial drug use in tertiary care hospital using defined daily dose and days of therapy.

Authors:  Dipika Bansal; S Mangla; K Undela; K Gudala; S D'Cruz; A Sachdev; P Tiwari
Journal:  Indian J Pharm Sci       Date:  2014-05       Impact factor: 0.975

10.  Trends of Antibiotic Consumption in Korea According to National Reimbursement Data (2008-2012): A Population-Based Epidemiologic Study.

Authors:  Young Kyung Yoon; Gi Chan Park; Hyonggin An; Byung Chul Chun; Jang Wook Sohn; Min Ja Kim
Journal:  Medicine (Baltimore)       Date:  2015-11       Impact factor: 1.817

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  2 in total

1.  Pattern of Antibiotic Use among Hospitalized Patients according to WHO Access, Watch, Reserve (AWaRe) Classification: Findings from a Point Prevalence Survey in Bangladesh.

Authors:  Md Mahbubur Rashid; Zubair Akhtar; Sukanta Chowdhury; Md Ariful Islam; Shahana Parveen; Probir Kumar Ghosh; Aninda Rahman; Zobaidul Haque Khan; Khaleda Islam; Nitish Debnath; Mahmudur Rahman; Fahmida Chowdhury
Journal:  Antibiotics (Basel)       Date:  2022-06-16

2.  Evaluation of antibiotic prescribing patterns among inpatients using World Health Organization indicators: A cross-sectional study.

Authors:  Tesfaye Yimer Tadesse; Mulugeta Molla; Yohannis Shumet Yimer; Benyas Shishigie Tarekegn; Belayneh Kefale
Journal:  SAGE Open Med       Date:  2022-05-14
  2 in total

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