Literature DB >> 34157555

Recent studies of nitrogen containing heterocyclic compounds as novel antiviral agents: A review.

Arif Mermer1, Turgut Keles2, Yakup Sirin3.   

Abstract

N-heterocycles are important, not only because of their abundance, but above all because of their chemical, biological and technical significance. They play an important role in biological investigation such as anticancer, antiinflammatory, antibacterial, antiviral, anti-tumor, antidiabetic, etc. In this study, we focused on examining synthesized some 5- or 6-ring N-heterocyclic compounds that showed the antiviral activity in last 5 years, and investigation of these compounds structure-activity relationship studies. This review will be useful to scientists in research fields of organic synthesis, medicinal chemistry, and pharmacology.
Copyright © 2021 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Antiviral activity; N-heterocyclic compound; Structure-activity relationship

Mesh：

Substances：

Year:  2021        PMID： 34157555     DOI： 10.1016/j.bioorg.2021.105076

Source DB:  PubMed          Journal:  Bioorg Chem        ISSN： 0045-2068            Impact factor:   5.275


  11 in total

Review 1.  Inhibitory potential of nitrogen, oxygen and sulfur containing heterocyclic scaffolds against acetylcholinesterase and butyrylcholinesterase.

Authors:  Rami J Obaid; Nafeesa Naeem; Ehsan Ullah Mughal; Munirah M Al-Rooqi; Amina Sadiq; Rabab S Jassas; Ziad Moussa; Saleh A Ahmed
Journal:  RSC Adv       Date:  2022-07-12       Impact factor: 4.036

2.  Synthesis and Bioactivities of Novel Galactoside Derivatives Containing 1,3,4-Thiadiazole Moiety.

Authors:  Yafei Shu; Meihang Chen; Daowang Lu; Zengyan Zhou; Jianhong Yu; Xiaoling Hu; Jiaqin Yang; Aiqin Li; Jianglong Liu; Hairong Luo
Journal:  Front Chem       Date:  2022-05-19       Impact factor: 5.545

3.  Utility of arylglyoxal hydrates in synthesis of 4-aroyl-[1,3,5]triazino[1,2-a]benzimidazol-2(1H)-imines and 5-aryl-2-phenyl-4H-imidazol-4-imines.

Authors:  Bahgat R M Hussein; Amr H Moustafa
Journal:  Mol Divers       Date:  2022-01-21       Impact factor: 2.943

4.  One-pot synthesis of new alkyl 1-naphthoates bearing quinoline, pyranone and cyclohexenone moieties via metal-free sequential addition/oxidation reactions.

Authors:  Seyedeh Hekmat Mousavi; Mohammad Reza Mohammadizadeh; Samira Poorsadeghi; Satoru Arimitsu; Fatemeh Mohammadsaleh; Genta Kojya; Shinichi Gima
Journal:  RSC Adv       Date:  2021-11-16       Impact factor: 4.036

Review 5.  Therapeutic potential of pyrrole and pyrrolidine analogs: an update.

Authors:  N Jeelan Basha; S M Basavarajaiah; K Shyamsunder
Journal:  Mol Divers       Date:  2022-01-25       Impact factor: 3.364

Review 6.  Biosafety chemistry and biosafety materials: A new perspective to solve biosafety problems.

Authors:  Yingjie Yu; Jianxun Ding; Yunhao Zhou; Haihua Xiao; Guizhen Wu
Journal:  Biosaf Health       Date:  2022-01-04

7.  Novel Pyridothienopyrimidine Derivatives: Design, Synthesis and Biological Evaluation as Antimicrobial and Anticancer Agents.

Authors:  Eman M Mohi El-Deen; Manal M Anwar; Amina A Abd El-Gwaad; Eman A Karam; Mohamed K El-Ashrey; Rafika R Kassab
Journal:  Molecules       Date:  2022-01-26       Impact factor: 4.411

8.  Discovery of Novel Quinazoline Derivatives as Potent Antitumor Agents.

Authors:  Zhenxi Niu; Shuli Ma; Lei Zhang; Qibing Liu; Shengnan Zhang
Journal:  Molecules       Date:  2022-06-17       Impact factor: 4.927

9.  Design, Synthesis, and Bioactivities of Novel Trifluoromethyl Pyrimidine Derivatives Bearing an Amide Moiety.

Authors:  Wenjun Lan; Xuemei Tang; Jia Yu; Qiang Fei; Wenneng Wu; Pei Li; Heng Luo
Journal:  Front Chem       Date:  2022-07-15       Impact factor: 5.545

Review 10.  Quinoline derivatives volunteering against antimicrobial resistance: rational approaches, design strategies, structure activity relationship and mechanistic insights.

Authors:  Nitish Kumar; Aanchal Khanna; Komalpreet Kaur; Harmandeep Kaur; Anchal Sharma; Preet Mohinder Singh Bedi
Journal:  Mol Divers       Date:  2022-10-05       Impact factor: 3.364
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