Literature DB >> 34152954

Cluster of Oseltamivir-Resistant and Hemagglutinin Antigenically Drifted Influenza A(H1N1)pdm09 Viruses, Texas, USA, January 2020.

Teena Mohan, Ha T Nguyen, Krista Kniss, Vasiliy P Mishin, Angiezel A Merced-Morales, Jennifer Laplante, Kirsten St George, Patricia Blevins, Anton Chesnokov, Juan A De La Cruz, Rebecca Kondor, David E Wentworth, Larisa V Gubareva.   

Abstract

Four cases of oseltamivir-resistant influenza A(H1N1)pdm09 virus infection were detected among inhabitants of a border detention center in Texas, USA. Hemagglutinin of these viruses belongs to 6B.1A5A-156K subclade, which may enable viral escape from preexisting immunity. Our finding highlights the necessity to monitor both drug resistance and antigenic drift of circulating viruses.

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Keywords:  Texas; United States; antigenic drift; antimicrobial resistance; drug resistance; influenza; influenza A(H1N1); neuraminidase inhibitor; transmission; viruses

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Year:  2021        PMID: 34152954     DOI: 10.3201/eid2707.204593

Source DB:  PubMed          Journal:  Emerg Infect Dis        ISSN: 1080-6040            Impact factor:   6.883


  2 in total

Review 1.  Global update on the susceptibilities of human influenza viruses to neuraminidase inhibitors and the cap-dependent endonuclease inhibitor baloxavir, 2018-2020.

Authors:  Elena A Govorkova; Emi Takashita; Rod S Daniels; Seiichiro Fujisaki; Lance D Presser; Mira C Patel; Weijuan Huang; Angie Lackenby; Ha T Nguyen; Dmitriy Pereyaslov; Aine Rattigan; Sook Kwan Brown; Magdi Samaan; Kanta Subbarao; Sun Wong; Dayan Wang; Richard J Webby; Hui-Ling Yen; Wenqing Zhang; Adam Meijer; Larisa V Gubareva
Journal:  Antiviral Res       Date:  2022-03-12       Impact factor: 10.103

2.  Assessing the fitness of a dual-antiviral drug resistant human influenza virus in the ferret model.

Authors:  Harry L Stannard; Edin J Mifsud; Steffen Wildum; Sook Kwan Brown; Paulina Koszalka; Takao Shishido; Satoshi Kojima; Shinya Omoto; Keiko Baba; Klaus Kuhlbusch; Aeron C Hurt; Ian G Barr
Journal:  Commun Biol       Date:  2022-09-28
  2 in total

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