Literature DB >> 34151216

Potential Application of Vaporized Drugs via Nasal Inhalers to Prevent Mortality and Central Nervous System Damage Caused by Primary Amoebic Meningoencephalitis Due to Naegleria fowleri.

Ruqaiyyah Siddiqui1, Mohamed Yehia Abouleish1, Mustafa Khamis1, Taleb Ibrahim1, Naveed Ahmed Khan2.   

Abstract

Here, it is proposed that nasal inhalers with specific anti-Naegleria fowleri drugs or a combination of anti-N. fowleri compounds combined with steroids such as dexamethasone could provide a practical solution for treating primary amoebic meningoencephalitis.
© 2021 American Chemical Society.

Entities:  

Year:  2021        PMID： 34151216      PMCID： PMC8205233          DOI： 10.1021/acsptsci.1c00086

Source DB:  PubMed          Journal:  ACS Pharmacol Transl Sci        ISSN： 2575-9108


  5 in total

1.  Intranasal delivery of obidoxime to the brain prevents mortality and CNS damage from organophosphate poisoning.

Authors:  Jishnu K S Krishnan; Peethambaran Arun; Abhilash P Appu; Nivetha Vijayakumar; Taíza H Figueiredo; Maria F M Braga; Sudikshya Baskota; Cara H Olsen; Natalia Farkas; John Dagata; William H Frey; John R Moffett; Aryan M A Namboodiri
Journal:  Neurotoxicology       Date:  2016-01-02       Impact factor: 4.294

2.  Acute pyogenic meningitis probably due to Acanthamoeba sp.: a preliminary report.

Authors:  M Fowler; R F Carter
Journal:  Br Med J       Date:  1965-09-25

Review 3.  Biology and pathogenesis of Naegleria fowleri.

Authors:  Ruqaiyyah Siddiqui; Ibne Karim M Ali; Jennifer R Cope; Naveed Ahmed Khan
Journal:  Acta Trop       Date:  2016-09-09       Impact factor: 3.112

4.  Liquid and vapour-phase antifungal activities of selected essential oils against Candida albicans: microscopic observations and chemical characterization of Cymbopogon citratus.

Authors:  Amit K Tyagi; Anushree Malik
Journal:  BMC Complement Altern Med       Date:  2010-11-10       Impact factor: 3.659

Review 5.  Nasal delivery of high molecular weight drugs.

Authors:  Yildiz Ozsoy; Sevgi Gungor; Erdal Cevher
Journal:  Molecules       Date:  2009-09-23       Impact factor: 4.411
  5 in total
  1 in total

1.  Antiamoebic Properties of Laboratory and Clinically Used Drugs against Naegleria fowleri and Balamuthia mandrillaris.

Authors:  Ruqaiyyah Siddiqui; Mohammad Ridwane Mungroo; Tengku Shahrul Anuar; Ahmad M Alharbi; Hasan Alfahemi; Adel B Elmoselhi; Naveed Ahmed Khan
Journal:  Antibiotics (Basel)       Date:  2022-05-31
  1 in total

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