Literature DB >> 34150396

Autoimmune Hepatitis With Concomitant Pernicious Anemia: A Rare Association.

Amir Riaz1, Sikandar Khan1, Rafael Miret1, Pablo Bejarano2, Asad Ur Rahman3.   

Abstract

The co-occurrence of autoimmune hepatitis (AIH) and pernicious anemia (PA) is extremely rare. We present a case of a 70-year-old woman with AIH who presented for the evaluation of poor appetite and weight loss. Laboratory studies were significant for microcytic anemia, B12, and iron deficiency. Esophagogastroduodenoscopy showed diffuse gastric mucosal atrophy, and the pathology from the body of the stomach showed chronic gastritis. Additional testing was positive for parietal cell antibody and intrinsic factor blocking antibody, confirming the diagnosis of PA. To the best of our knowledge, there is only one documented case of AIH associated with PA.
Copyright © 2021, Riaz et al.

Entities:  

Keywords:  autoimmune hepatitis; intrinsic factor blocking antibody; parietal cell antibody; pernicious anemia

Year:  2021        PMID: 34150396      PMCID: PMC8203103          DOI: 10.7759/cureus.15045

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  10 in total

1.  Autoimmune hepatitis, autoimmune gastritis, and gastric carcinoid in a type 1 diabetic patient: a case report.

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2.  Cancer Risk After Pernicious Anemia in the US Elderly Population.

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Authors:  M Cojocaru; Inimioara Mihaela Cojocaru; Isabela Silosi
Journal:  Maedica (Buchar)       Date:  2010-04

4.  Concurrent autoimmune diseases in patients with autoimmune hepatitis.

Authors:  Andreas Teufel; Arndt Weinmann; George J Kahaly; Catherine Centner; Anja Piendl; Marcus Wörns; Ansgar W Lohse; Peter R Galle; Stephan Kanzler
Journal:  J Clin Gastroenterol       Date:  2010-03       Impact factor: 3.062

Review 5.  Pernicious anemia: new insights from a gastroenterological point of view.

Authors:  Edith Lahner; Bruno Annibale
Journal:  World J Gastroenterol       Date:  2009-11-07       Impact factor: 5.742

6.  HLA antigen expression in autoimmune endocrinopathies.

Authors:  P Hrdá; I Sterzl; P Matucha; F Korioth; A Kromminga
Journal:  Physiol Res       Date:  2004       Impact factor: 1.881

Review 7.  Extrahepatic Autoimmune Diseases in Patients with Autoimmune Liver Diseases: A Phenomenon Neglected by Gastroenterologists.

Authors:  Liping Guo; Lu Zhou; Na Zhang; Baoru Deng; Bangmao Wang
Journal:  Gastroenterol Res Pract       Date:  2017-01-16       Impact factor: 2.260

8.  Association pernicious anemia and autoimmune polyendocrinopathy: a retrospective study.

Authors:  A A Zulfiqar; E Andres
Journal:  J Med Life       Date:  2017 Oct-Dec

9.  Current concepts on gastric carcinoid tumors.

Authors:  George C Nikou; Theodoros P Angelopoulos
Journal:  Gastroenterol Res Pract       Date:  2012-12-17       Impact factor: 2.260

10.  Carcinoïd tumor revealing pernicious anemia.

Authors:  Neirouz Ghannouchi Jaafoura; Ahlem Braham Krifa
Journal:  Pan Afr Med J       Date:  2014-10-15
  10 in total

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