Yanshu Xu1, Jiang Wu2, Jili Zhao3, Haiping Zhang4. 1. Department of Anesthesiology, Fengcheng Hospital Fengxian District, Shanghai 201411, China. 2. Department of Anesthesiology, Ninety-ninth Hospital of The Joint Support Unit Zhangzhou 363000, Fujian Province, China. 3. Department of Anesthesiology, Zhangqiu District Maternal and Child Health Hospital Jinan 250200, Shandong Province, China. 4. Department of Anesthesiology, Sichuan Provincial Maternity and Child Health Care Health Hospital Chengdu 610045, Sichuan Province, China.
Abstract
OBJECTIVE: To study the effect of propofol combined with remifentanil on hemodynamics and anesthetic effect in patients undergoing laparoscopic ovarian cystectomy under laryngeal mask airway (LMA) anesthesia. METHODS:From December 2018 to December 2019, gynecological patients who underwentlaparoscopic ovarian cystectomy in our hospital were chosen and randomly separated into control group (group A) and combination group (group B). In the group B, patients were anesthetized with remifentanil combined with propofol. In the group A, patients were anesthetized with fentanyl combined with propofol. The anesthetic effect, hemodynamic changes, alertness-sedation score (OAAS), verbal depiction score (VRA), postoperative VAS score and adverse reactions were observed and compared in both groups. RESULTS: The anesthesia induction time, recovery time of postoperative spontaneous respiration, time of opening eyes and time of removing laryngeal mask in the group B were shorter than those in the group A, and the difference was statistically significant (P<0.05). The OAAS scores at the time of recovery and 5 min after laryngeal mask removal in the group B were obviously lower than those in the group A. The mean arterial pressure and heart rate before and after 40 min pneumoperitoneum were more stable than those in the group A. The degree of postoperative pain in the group B was also significantly weaker than that in the group A. The incidence of postoperative adverse reactions was also lower than that of the group A, and the difference was statistically significant (P<0.05). CONCLUSION:Propofol combined with remifentanil and LMA anesthesia has better anesthetic effect, more stable condition and higher safety for patients undergoing laparoscopic ovarian cystectomy. AJTR
RCT Entities:
OBJECTIVE: To study the effect of propofol combined with remifentanil on hemodynamics and anesthetic effect in patients undergoing laparoscopic ovarian cystectomy under laryngeal mask airway (LMA) anesthesia. METHODS: From December 2018 to December 2019, gynecological patients who underwent laparoscopic ovarian cystectomy in our hospital were chosen and randomly separated into control group (group A) and combination group (group B). In the group B, patients were anesthetized with remifentanil combined with propofol. In the group A, patients were anesthetized with fentanyl combined with propofol. The anesthetic effect, hemodynamic changes, alertness-sedation score (OAAS), verbal depiction score (VRA), postoperative VAS score and adverse reactions were observed and compared in both groups. RESULTS: The anesthesia induction time, recovery time of postoperative spontaneous respiration, time of opening eyes and time of removing laryngeal mask in the group B were shorter than those in the group A, and the difference was statistically significant (P<0.05). The OAAS scores at the time of recovery and 5 min after laryngeal mask removal in the group B were obviously lower than those in the group A. The mean arterial pressure and heart rate before and after 40 min pneumoperitoneum were more stable than those in the group A. The degree of postoperative pain in the group B was also significantly weaker than that in the group A. The incidence of postoperative adverse reactions was also lower than that of the group A, and the difference was statistically significant (P<0.05). CONCLUSION:Propofol combined with remifentanil and LMA anesthesia has better anesthetic effect, more stable condition and higher safety for patients undergoing laparoscopic ovarian cystectomy. AJTR
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