Jianfu Han1, Zhongyou Zeng1, Fei Pei1, Ting Zheng2. 1. Department of Orthopedics, China Coast Guard Hospital of The People's Armed Police Force Jiaxing 314000, Zhejiang, China. 2. Department of Anesthesiology, China Coast Guard Hospital of The People's Armed Police Force Jiaxing 314000, Zhejiang, China.
Abstract
OBJECTIVE: To analyze the clinical effects of periarticular knee osteotomy (PKO) in the treatment of knee osteoarthritis (KOA). METHODS: A total of 180 patients with KOA admitted to our hospital were selected as the study subjects, and were divided into study group (90 cases) and control group (90 cases) in accordance with different intervention measures. The study group was treated with PKO, while the control group was treated with joint replacement. The perioperative indices, and postoperative pain degrees, knee joint function, quality of life, inflammatory factors and complications were compared between the two groups. RESULTS: The control group was superior to the study group regarding the amount of preoperative bleeding, surgical duration, and incidence rate of complications, while the study group was superior to the control group regarding the long-term (over 2 years) knee joint function and quality of life (P < 0.05). There was no marked difference in the postoperative pain degrees and preoperative and postoperative levels of inflammatory factors between the two groups (P < 0.05). CONCLUSION:PKO, exhibiting a high safety profile, can remarkably improve the joint pain symptoms, knee joint function, quality of life and symptoms of KOA in patients with KOA. Therefore, PKO is worthy of clinical promotion and implementation. AJTR
RCT Entities:
OBJECTIVE: To analyze the clinical effects of periarticular knee osteotomy (PKO) in the treatment of knee osteoarthritis (KOA). METHODS: A total of 180 patients with KOA admitted to our hospital were selected as the study subjects, and were divided into study group (90 cases) and control group (90 cases) in accordance with different intervention measures. The study group was treated with PKO, while the control group was treated with joint replacement. The perioperative indices, and postoperative pain degrees, knee joint function, quality of life, inflammatory factors and complications were compared between the two groups. RESULTS: The control group was superior to the study group regarding the amount of preoperative bleeding, surgical duration, and incidence rate of complications, while the study group was superior to the control group regarding the long-term (over 2 years) knee joint function and quality of life (P < 0.05). There was no marked difference in the postoperative pain degrees and preoperative and postoperative levels of inflammatory factors between the two groups (P < 0.05). CONCLUSION: PKO, exhibiting a high safety profile, can remarkably improve the joint pain symptoms, knee joint function, quality of life and symptoms of KOA in patients with KOA. Therefore, PKO is worthy of clinical promotion and implementation. AJTR
Authors: Catherine Legrand; Usman Ahmed; Attia Anwar; Kashif Rajpoot; Sabah Pasha; Cécile Lambert; Rose K Davidson; Ian M Clark; Paul J Thornalley; Yves Henrotin; Naila Rabbani Journal: Arthritis Res Ther Date: 2018-06-22 Impact factor: 5.156
Authors: Tereza Kropáčková; Olga Šléglová; Olga Růžičková; Jiří Vencovský; Karel Pavelka; Ladislav Šenolt Journal: BMC Musculoskelet Disord Date: 2018-07-27 Impact factor: 2.362