Literature DB >> 34149992

Stem cell transplantation for treating liver diseases: progress and remaining challenges.

Shanshan Li1,2, Yanzhen Bi3, Zhongping Duan1,2, Yongkai Chang4, Feng Hong5, Yu Chen1,2.   

Abstract

With the development of regenerative medicine, various stem cells are increasingly considered for treating liver diseases. Various stem cells have been reported to play an essential role in liver recovery, and studies have verified the preliminary effectiveness and safety of these therapies. Stem cell-based therapies will emerge as an effective treatment strategy for liver diseases. Thus, the research progress and challenges to the related stem cells were reviewed, namely the classification of stem cells, cell culture, transplantation, cell tracing in the body, therapies for various liver diseases. AJTR
Copyright © 2021.

Entities:  

Keywords:  Stem cell; liver diseases; therapy; transplantation

Year:  2021        PMID： 34149992      PMCID： PMC8205777     

Source DB:  PubMed          Journal:  Am J Transl Res        ISSN： 1943-8141            Impact factor:   4.060


  87 in total

Review 1.  Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities.

Authors:  Jacques Galipeau; Luc Sensébé
Journal:  Cell Stem Cell       Date:  2018-06-01       Impact factor: 24.633

Review 2.  Biological functions of mesenchymal stem cells and clinical implications.

Authors:  Abderrahim Naji; Masamitsu Eitoku; Benoit Favier; Frédéric Deschaseaux; Nathalie Rouas-Freiss; Narufumi Suganuma
Journal:  Cell Mol Life Sci       Date:  2019-05-04       Impact factor: 9.261

Review 3.  Stem cell therapies for liver failure and cirrhosis.

Authors:  Zheng Zhang; Fu-Sheng Wang
Journal:  J Hepatol       Date:  2013-01-23       Impact factor: 25.083

4.  Granulocyte colony-stimulating factor mobilizes CD34(+) cells and improves survival of patients with acute-on-chronic liver failure.

Authors:  Vishal Garg; Hitendra Garg; Arshi Khan; Nirupama Trehanpati; Ashish Kumar; Barjesh Chander Sharma; Puja Sakhuja; Shiv Kumar Sarin
Journal:  Gastroenterology       Date:  2011-11-23       Impact factor: 22.682

5.  Transplanted mouse liver stem cells at different stages of differentiation ameliorate concanavalin A-induced acute liver injury by modulating Tregs and Th17 cells in mice.

Authors:  Shanshan Li; Yanzhen Bi; Quanquan Wang; Manman Xu; Zhenglai Ma; Yonghong Yang; Yongkai Chang; Suling Chen; Derong Liu; Zhongping Duan; Feng Hong; Yu Chen
Journal:  Am J Transl Res       Date:  2019-12-15       Impact factor: 4.060

6.  Characterization and clinical application of human CD34+ stem/progenitor cell populations mobilized into the blood by granulocyte colony-stimulating factor.

Authors:  Myrtle Y Gordon; Natasa Levicar; Madhava Pai; Philippe Bachellier; Ioannis Dimarakis; Faisal Al-Allaf; Hanane M'Hamdi; Tamara Thalji; Jonathan P Welsh; Stephen B Marley; John Davies; Francesco Dazzi; Federica Marelli-Berg; Paul Tait; Raymond Playford; Long Jiao; Steen Jensen; Joanna P Nicholls; Ahmet Ayav; Mahrokh Nohandani; Farzin Farzaneh; Joop Gaken; Rikke Dodge; Malcolm Alison; Jane F Apperley; Robert Lechler; Nagy A Habib
Journal:  Stem Cells       Date:  2006-03-23       Impact factor: 6.277

Review 7.  Historical Perspectives and Advances in Mesenchymal Stem Cell Research for the Treatment of Liver Diseases.

Authors:  Chien-Wei Lee; Yu-Fan Chen; Hao-Hsiang Wu; Oscar K Lee
Journal:  Gastroenterology       Date:  2017-10-26       Impact factor: 22.682

8.  Human mesenchymal stem cell transfusion is safe and improves liver function in acute-on-chronic liver failure patients.

Authors:  Ming Shi; Zheng Zhang; Ruonan Xu; Hu Lin; Junliang Fu; Zhengsheng Zou; Aimin Zhang; Jianfei Shi; Liming Chen; Sa Lv; Weiping He; Hua Geng; Lei Jin; Zhenwen Liu; Fu-Sheng Wang
Journal:  Stem Cells Transl Med       Date:  2012-10-11       Impact factor: 6.940

9.  A pooled analysis of mesenchymal stem cell-based therapy for liver disease.

Authors:  Lu Zhao; Shanquan Chen; Xiaowei Shi; Hongcui Cao; Lanjuan Li
Journal:  Stem Cell Res Ther       Date:  2018-03-21       Impact factor: 6.832

10.  Mesenchymal Stem Cells and Induced Bone Marrow-Derived Macrophages Synergistically Improve Liver Fibrosis in Mice.

Authors:  Yusuke Watanabe; Atsunori Tsuchiya; Satoshi Seino; Yuzo Kawata; Yuichi Kojima; Shunzo Ikarashi; Philip J Starkey Lewis; Wei-Yu Lu; Junichi Kikuta; Hirokazu Kawai; Satoshi Yamagiwa; Stuart J Forbes; Masaru Ishii; Shuji Terai
Journal:  Stem Cells Transl Med       Date:  2018-11-05       Impact factor: 6.940
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  1 in total

Review 1.  Adult stem cell transplantation combined with conventional therapy for the treatment of end-stage liver disease: a systematic review and meta-analysis.

Authors:  Chen-Hui Zhu; Dian-Han Zhang; Chen-Wei Zhu; Jing Xu; Chuan-Long Guo; Xiang-Gen Wu; Qi-Long Cao; Guo-Hu Di
Journal:  Stem Cell Res Ther       Date:  2021-10-30       Impact factor: 6.832
  1 in total

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