Literature DB >> 3414622

Sublingual lorazepam in childhood serial seizures.

J Y Yager1, S S Seshia.   

Abstract

Sublingual lorazepam was successful in controlling serial seizures in ten children. There was both intrasubject and intersubject variability in the effective dose, which ranged from about 0.05 mg/kg to 0.15 mg/kg. Side effects were minimal and consisted of drowsiness, unsteadiness, nausea, and hyperactivity. Sublingual lorazepam is an easy and effective way to treat serial seizures at home.

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Year:  1988        PMID: 3414622     DOI: 10.1001/archpedi.1988.02150090029016

Source DB:  PubMed          Journal:  Am J Dis Child        ISSN: 0002-922X


  5 in total

1.  Pharmacokinetics of buccal and intranasal lorazepam in healthy adult volunteers.

Authors:  Mark Anderson; Parag Tambe; Helen Sammons; Hussain Mulla; Richard Cole; Imti Choonara
Journal:  Eur J Clin Pharmacol       Date:  2011-08-12       Impact factor: 2.953

2.  Comparison of intranasal midazolam with intravenous diazepam for treating febrile seizures in children: prospective randomised study.

Authors:  E Lahat; M Goldman; J Barr; T Bistritzer; M Berkovitch
Journal:  BMJ       Date:  2000-07-08

Review 3.  Clinical practice: the treatment of acute convulsive seizures in children.

Authors:  Lieven Lagae
Journal:  Eur J Pediatr       Date:  2011-02-08       Impact factor: 3.183

Review 4.  Oral mucosal drug delivery: clinical pharmacokinetics and therapeutic applications.

Authors:  Hao Zhang; Jie Zhang; James B Streisand
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

Review 5.  Rescue therapies for seizure emergencies: current and future landscape.

Authors:  Debopam Samanta
Journal:  Neurol Sci       Date:  2021-07-16       Impact factor: 3.830

  5 in total

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