Literature DB >> 34146208

Transgender Youth Executive Functioning: Relationships with Anxiety Symptoms, Autism Spectrum Disorder, and Gender-Affirming Medical Treatment Status.

John F Strang1,2,3,4,5, Diane Chen6,7,8,9,10, Eric Nelson11,12, Scott F Leibowitz13,14, Leena Nahata11,12,15, Laura G Anthony16,17, Amber Song18,19,20, Connor Grannis11, Elizabeth Graham21, Shane Henise18,22, Eric Vilain23,24,25, Eleonora Sadikova26, Andrew Freeman27,28, Cara Pugliese19,20, Ayesha Khawaja29,18,19, Tekla Maisashvili29,18,19, Michael Mancilla22, Lauren Kenworthy19,30,20.   

Abstract

Executive function (EF) underlies broad health and adaptive outcomes. For transgender youth, navigating gender discernment and gender affirmation demand EF. Yet, factors associated with transgender youth EF are unknown. We investigate hypothesized predictors of EF: over-represented conditions among transgender youth (anxiety and depression symptoms, autism spectrum disorder [ASD]) and gender-affirming care. One-hundred twenty-four transgender 11-21-year-olds participated. Parents/caregivers completed EF and mental health report measures. ASD diagnostics and gender-affirming medication histories were collected. 21 % of non-autistic and 69 % of autistic transgender youth had clinically elevated EF problems. Membership in the gender-affirming hormone treatment group was associated with better EF. ASD, anxiety symptoms, and membership in the long-duration pubertal suppression group were associated with poorer EF. Given the importance of EF skills for multiple outcomes, and the unique and additional EF demands specific to transgender youths' experiences, EF skill monitoring-and when appropriate, supports-should be considered for transgender youth.
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Autistic; Executive function; Gender affirming hormones; Gender diversity; Internalizing

Mesh:

Substances:

Year:  2021        PMID: 34146208     DOI: 10.1007/s10578-021-01195-6

Source DB:  PubMed          Journal:  Child Psychiatry Hum Dev        ISSN: 0009-398X


  72 in total

1.  Meta-analytic evidence for a superordinate cognitive control network subserving diverse executive functions.

Authors:  Tara A Niendam; Angela R Laird; Kimberly L Ray; Y Monica Dean; David C Glahn; Cameron S Carter
Journal:  Cogn Affect Behav Neurosci       Date:  2012-06       Impact factor: 3.282

Review 2.  On the evolutionary origins of executive functions.

Authors:  Alfredo Ardila
Journal:  Brain Cogn       Date:  2008-04-07       Impact factor: 2.310

3.  Subjective Executive Function Weaknesses Are Linked to Elevated Internalizing Symptoms Among Community Adolescents.

Authors:  Benjamin C Mullin; Emmaly L Perks; Dustin A Haraden; Hannah R Snyder; Benjamin L Hankin
Journal:  Assessment       Date:  2018-12-22

Review 4.  Executive functions.

Authors:  Adele Diamond
Journal:  Annu Rev Psychol       Date:  2012-09-27       Impact factor: 24.137

5.  Executive function and other cognitive deficits are distal risk factors of generalized anxiety disorder 9 years later.

Authors:  Nur Hani Zainal; Michelle G Newman
Journal:  Psychol Med       Date:  2017-12-11       Impact factor: 7.723

6.  Cognitive inflexibility and suicidal ideation: mediating role of brooding and hopelessness.

Authors:  Regina Miranda; Jorge Valderrama; Aliona Tsypes; Erin Gadol; Michelle Gallagher
Journal:  Psychiatry Res       Date:  2013-03-23       Impact factor: 3.222

7.  Executive Function and Psychosocial Quality of Life in School Age Children with Congenital Heart Disease.

Authors:  Jacqueline H Sanz; Jichuan Wang; Madison M Berl; Anna C Armour; Yao I Cheng; Mary T Donofrio
Journal:  J Pediatr       Date:  2018-09-19       Impact factor: 4.406

8.  Everyday executive function predicts adaptive and internalizing behavior among children with and without autism spectrum disorder.

Authors:  Emily Gardiner; Grace Iarocci
Journal:  Autism Res       Date:  2017-09-27       Impact factor: 5.216

9.  Childhood executive function continues to predict outcomes in young adult females with and without childhood-diagnosed ADHD.

Authors:  Meghan Miller; Adriana J Nevado-Montenegro; Stephen P Hinshaw
Journal:  J Abnorm Child Psychol       Date:  2012-07

Review 10.  A Bidirectional Relationship between Executive Function and Health Behavior: Evidence, Implications, and Future Directions.

Authors:  Julia L Allan; David McMinn; Michael Daly
Journal:  Front Neurosci       Date:  2016-08-23       Impact factor: 4.677

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  1 in total

1.  The lived experience of gender dysphoria in autistic young people: a phenomenological study with young people and their parents.

Authors:  Kate Cooper; Catherine Butler; Ailsa Russell; William Mandy
Journal:  Eur Child Adolesc Psychiatry       Date:  2022-04-04       Impact factor: 4.785

  1 in total

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