Mariapaola Giordano1, Daniela Montorio1, Marina Concilio1, Vincenzo Brescia Morra1, Gilda Cennamo2. 1. Department of Neurosciences, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy. 2. Department of Public Health, University of Naples Federico II, Via S. Pansini 5, 80133, Naples, Italy. xgilda@hotmail.com.
Abstract
INTRODUCTION/AIMS: Non-arteritic anterior ischemic optic neuropathy (NAION) is an acute infarction of the prelaminar anterior optic disc, resulting from the occlusion of posterior ciliary arteries. Here, we evaluated the correlation between structural and vascular features in a case of resolved NAION. METHODS: Observational case report. RESULTS: A 50-year-old male patient was referred at an Eye clinic due to an altitudinal visual field defect in the left eye, occurred 9 months before. Fundus examination was unremarkable, while structural SD-OCT reveals retinal nerve fiber layer (RNFL), ganglion cell complex (GCC) thinning associated with reduction of peripapillary vascular density at OCT Angiography. DISCUSSION: We found a precise spatial correlation among RNFL and GCC thinning, peripapillary vascular reduction and visual field defects. This case demonstrates that OCTA represents a new, valid and non-invasive imaging technique in the diagnosis and follow-up of NAION, even after the resolution of the acute phase, in the absence of clinical signs at fundus examination.
INTRODUCTION/AIMS: Non-arteritic anterior ischemic optic neuropathy (NAION) is an acute infarction of the prelaminar anterior optic disc, resulting from the occlusion of posterior ciliary arteries. Here, we evaluated the correlation between structural and vascular features in a case of resolved NAION. METHODS: Observational case report. RESULTS: A 50-year-old male patient was referred at an Eye clinic due to an altitudinal visual field defect in the left eye, occurred 9 months before. Fundus examination was unremarkable, while structural SD-OCT reveals retinal nerve fiber layer (RNFL), ganglion cell complex (GCC) thinning associated with reduction of peripapillary vascular density at OCT Angiography. DISCUSSION: We found a precise spatial correlation among RNFL and GCC thinning, peripapillary vascular reduction and visual field defects. This case demonstrates that OCTA represents a new, valid and non-invasive imaging technique in the diagnosis and follow-up of NAION, even after the resolution of the acute phase, in the absence of clinical signs at fundus examination.
Authors: Gema Rebolleda; Laura Díez-Álvarez; Yoel García Marín; Victoria de Juan; Francisco J Muñoz-Negrete Journal: Ophthalmologica Date: 2018-06-26 Impact factor: 3.250
Authors: Harsha L Rao; Zia S Pradhan; Robert N Weinreb; Hemanth B Reddy; Mohammed Riyazuddin; Srilakshmi Dasari; Meena Palakurthy; Narendra K Puttaiah; Dhanaraj A S Rao; Carroll A B Webers Journal: Am J Ophthalmol Date: 2016-08-30 Impact factor: 5.258