Fazel Karimzadeh1, Seyed Masoud Sajedi2, Saman Taram3, Fathemeh Karimzadeh4. 1. Postgraduate student, Department of Prosthodontics, Faculty of Dentistry, Shahed University, Tehran, Iran. 2. Postgraduate student, Department of Oral and Maxillofacial Medicine, Faculty of Dentistry, Shahed University, Tehran, Iran. 3. Dental student, Faculty of Dentistry, Urmia University of Medical Science, Urmia, Iran. 4. Faculty of Medical, Yasuj University of Medical Sciences, Yasuj, Iran. Electronic address: Fatimakmz71@gmail.com.
Abstract
STATEMENT OF PROBLEM: In the outbreak of COVID-19, coinfections and even superinfections in the background of SARS-CoV-2 viral infection have been reported. Such bacterial and fungal strains may be colonized in different tissues and organs, including the oral cavity. Whether infection with COVID-19 could increase colonization of different bacterial strains on removable dental prostheses is unclear. PURPOSE: The purpose of this clinical study was to compare bacterial colonization on removable dental prostheses in patients with COVID-19, before versus after diagnosis. MATERIAL AND METHODS: Two sex- and age-matched groups of complete-denture-wearing participants (N=60) with and without a positive diagnosis for COVID-19 were enrolled in the study. Swabs were used at 2 different time intervals to sample areas of the dentures, which were then cultured and the colony smears Gram stained. A statistical analysis was conducted by using the Mann-Whitney U test (α=.05). RESULTS: Streptococcus species (93.3% versus 40.0%, P=.047) and Klebsiella pneumonia (46.7% versus 13.4%, P=.036) were detected more frequently in the COVID-19-positive group. CONCLUSIONS: Higher rates of bacterial colonization, especially with Streptococcus species and Klebsiella pneumonia, were detected on removable dental prostheses after COVID-19 infection.
STATEMENT OF PROBLEM: In the outbreak of COVID-19, coinfections and even superinfections in the background of SARS-CoV-2 viral infection have been reported. Such bacterial and fungal strains may be colonized in different tissues and organs, including the oral cavity. Whether infection with COVID-19 could increase colonization of different bacterial strains on removable dental prostheses is unclear. PURPOSE: The purpose of this clinical study was to compare bacterial colonization on removable dental prostheses in patients with COVID-19, before versus after diagnosis. MATERIAL AND METHODS: Two sex- and age-matched groups of complete-denture-wearing participants (N=60) with and without a positive diagnosis for COVID-19 were enrolled in the study. Swabs were used at 2 different time intervals to sample areas of the dentures, which were then cultured and the colony smears Gram stained. A statistical analysis was conducted by using the Mann-Whitney U test (α=.05). RESULTS: Streptococcus species (93.3% versus 40.0%, P=.047) and Klebsiella pneumonia (46.7% versus 13.4%, P=.036) were detected more frequently in the COVID-19-positive group. CONCLUSIONS: Higher rates of bacterial colonization, especially with Streptococcus species and Klebsiella pneumonia, were detected on removable dental prostheses after COVID-19infection.
Authors: Livia Barenghi; Alberto Barenghi; Umberto Garagiola; Alberto Di Blasio; Aldo Bruno Giannì; Francesco Spadari Journal: Sensors (Basel) Date: 2021-12-22 Impact factor: 3.576