Nazanin Daneshvarhashjin1,2, Mahmoud Chizari3,4, Javad Mortazavi5, Gholamreza Rouhi6. 1. Faculty of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran. 2. Institute for Orthopaedic Research and Training, Department of Biomedical science, Faculty of Medicine, Katholieke Universiteit Leuven, Leuven, Belgium. 3. Faculty of Mechanical Engineering, Sharif University of Technology, Tehran, Iran. 4. School of Physics, Engineering and Computer Sciences, University of Hertfordshire, Hatfield, UK. 5. Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran. 6. Faculty of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran. grouhi@aut.ac.ir.
Abstract
BACKGROUND: Superior biomechanical performance of tapered interference screws, compared with non-tapered screws, with reference to the anterior cruciate ligament (ACL) reconstruction process, has been reported in the literature. However, the effect of tapered interference screw's body slope on the initial stability of ACL is poorly understood. Thus, the main goal of this study was to investigate the effect of the interference screw's body slope on the initial stability of the reconstructed ACL. METHODS: Based on the best screw-bone tunnel diameter ratios in non-tapered screws, two different tapered interference screws were designed and fabricated. The diameters of both screws were equal to bone tunnel diameter in one-third of their length from screw tip, then they were gradually increased by 1mm, in the lower slope (LSTIS), and 2 mm, in the higher slope (HSTIS) screws. To simulate the ACL reconstruction, sixteen soft tissue grafts were fixed, using HSTIS and LSTIS, in synthetic bone blocks. Through applying sub-failure cyclic incremental tensile load, graft-bone-screw construct's stiffness and graft laxity in each cycle, also through applying subsequent step of loading graft to the failure, maximum load to failure, and graft's mode of failure were determined. Accordingly, the performance of the fabricated interference screws was compared with each other. RESULTS: HSTIS provides a greater graft-bone-screw construct stiffness, and a lower graft laxity, compared to LSTIS. Moreover, transverse rupture of graft fibers for LSTIS, and necking of graft in the HSTIS group were the major types of grafts' failure. CONCLUSIONS: HSTIS better replicates the intact ACL's behavior, compared to LSTIS, by causing less damage in graft's fibers; reducing graft laxity; and increasing fixation stability. Nonetheless, finding the optimal slope remains as an unknown and can be the subject of future studies.
BACKGROUND: Superior biomechanical performance of tapered interference screws, compared with non-tapered screws, with reference to the anterior cruciate ligament (ACL) reconstruction process, has been reported in the literature. However, the effect of tapered interference screw's body slope on the initial stability of ACL is poorly understood. Thus, the main goal of this study was to investigate the effect of the interference screw's body slope on the initial stability of the reconstructed ACL. METHODS: Based on the best screw-bone tunnel diameter ratios in non-tapered screws, two different tapered interference screws were designed and fabricated. The diameters of both screws were equal to bone tunnel diameter in one-third of their length from screw tip, then they were gradually increased by 1mm, in the lower slope (LSTIS), and 2 mm, in the higher slope (HSTIS) screws. To simulate the ACL reconstruction, sixteen soft tissue grafts were fixed, using HSTIS and LSTIS, in synthetic bone blocks. Through applying sub-failure cyclic incremental tensile load, graft-bone-screw construct's stiffness and graft laxity in each cycle, also through applying subsequent step of loading graft to the failure, maximum load to failure, and graft's mode of failure were determined. Accordingly, the performance of the fabricated interference screws was compared with each other. RESULTS: HSTIS provides a greater graft-bone-screw construct stiffness, and a lower graft laxity, compared to LSTIS. Moreover, transverse rupture of graft fibers for LSTIS, and necking of graft in the HSTIS group were the major types of grafts' failure. CONCLUSIONS: HSTIS better replicates the intact ACL's behavior, compared to LSTIS, by causing less damage in graft's fibers; reducing graft laxity; and increasing fixation stability. Nonetheless, finding the optimal slope remains as an unknown and can be the subject of future studies.
Entities:
Keywords:
ACL Injury and Reconstruction; Bio-mimicked Interference Screw; Body Slope; Graft Damage; Graft Laxity; In-vitro Mechanical Tests; Initial Stability