Literature DB >> 34144200

Challenges in the management of chronic wound infections.

Marco Falcone1, Barbara De Angelis2, Federico Pea3, Alessandro Scalise4, Stefania Stefani5, Rolando Tasinato6, Orazio Zanetti7, Luca Dalla Paola8.   

Abstract

OBJECTIVES: Chronic wound infections may delay the healing process and are responsible for a significant burden on healthcare systems. Since inappropriate management may commonly occur in the care of these patients, this review aims to provide a practical guide underlining actions to avoid in the management of chronic wound infections.
METHODS: We performed a systematic review of the literature available in PubMed in the last 10 years, identifying studies regarding the management of patients with chronic wound infections. A panel of experts discussed the potential malpractices in this area. A list of 'Don'ts', including the main actions to be avoided, was drawn up using the 'Choosing Wisely' methodology.
RESULTS: In this review, we proposed a list of actions to avoid for optimal management of patients with chronic wound infections. Adequate wound bed preparation and wound antisepsis should be combined, as the absence of one of them leads to delayed healing and a higher risk of wound complications. Moreover, avoiding inappropriate use of systemic antibiotics is an important point because of the risk of selection of multidrug-resistant organisms as well as antibiotic-related adverse events.
CONCLUSION: A multidisciplinary team of experts in different fields (surgeon, infectious disease expert, microbiologist, pharmacologist, geriatrician) is required for the optimal management of chronic wound infections. Implementation of this approach may be useful to improve the management of patients with chronic wound infections.
Copyright © 2021 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  Antisepsis; Antiseptic agent; Chronic wound infection; Wound; Wound healing

Year:  2021        PMID: 34144200     DOI: 10.1016/j.jgar.2021.05.010

Source DB:  PubMed          Journal:  J Glob Antimicrob Resist        ISSN: 2213-7165            Impact factor:   4.035


  7 in total

Review 1.  Challenges and innovations in treating chronic and acute wound infections: from basic science to clinical practice.

Authors:  Xiaotong Ding; Qinghan Tang; Zeyu Xu; Ye Xu; Hao Zhang; Dongfeng Zheng; Shuqin Wang; Qian Tan; Joanneke Maitz; Peter K Maitz; Shaoping Yin; Yiwei Wang; Jun Chen
Journal:  Burns Trauma       Date:  2022-05-21

2.  Contribution of Topical Agents such as Hyaluronic Acid and Silver Sulfadiazine to Wound Healing and Management of Bacterial Biofilm.

Authors:  Francesco De Francesco; Michele Riccio; Shiro Jimi
Journal:  Medicina (Kaunas)       Date:  2022-06-20       Impact factor: 2.948

3.  What COVID-19 taught us: New opportunities and pathways from telemedicine and novel antiseptics in wound healing.

Authors:  Alessandro Scalise; Marco Falcone; Giampiero Avruscio; Enrico Brocco; Eugenio Ciacco; Aurora Parodi; Rolando Tasinato; Elia Ricci
Journal:  Int Wound J       Date:  2021-10-02       Impact factor: 3.099

Review 4.  The role of debridement in wound bed preparation in chronic wound: A narrative review.

Authors:  Deena Clare Thomas; Chong Li Tsu; Rose A Nain; Norkiah Arsat; Soong Shui Fun; Nik Amin Sahid Nik Lah
Journal:  Ann Med Surg (Lond)       Date:  2021-10-04

5.  Effects of Adipose-Derived Stem Cells and Their Conditioned Medium in a Human Ex Vivo Wound Model.

Authors:  Xiao Guo; Christoph Schaudinn; Ulrike Blume-Peytavi; Annika Vogt; Fiorenza Rancan
Journal:  Cells       Date:  2022-04-02       Impact factor: 6.600

6.  Hyaluronic Acid/Collagenase Ointment in the Treatment of Chronic Hard-to-Heal Wounds: An Observational and Retrospective Study.

Authors:  Francesco De Francesco; Marialuisa De Francesco; Michele Riccio
Journal:  J Clin Med       Date:  2022-01-21       Impact factor: 4.241

7.  Effect of Moringa oleifera Leaf Extract on Excision Wound Infections in Rats: Antioxidant, Antimicrobial, and Gene Expression Analysis.

Authors:  Abdullah A Al-Ghanayem; Mohammed Sanad Alhussaini; Mohammed Asad; Babu Joseph
Journal:  Molecules       Date:  2022-07-13       Impact factor: 4.927

  7 in total

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