Assaf Rozenberg1, Aviel Hadad2, Alon Peled3, Biana Dubinsky-Pertzov3, Lior Or3, Eva Eting3, Shai Efrati4, Eran Pras3, Adi Einan-Lifshitz3. 1. Department of Ophthalmology, Shamir Medical Center, Zerifin, Israel. assafroz@gmail.com. 2. Department of Ophthalmology, Soroka Medical Center, Be'ersheba, Israel. 3. Department of Ophthalmology, Shamir Medical Center, Zerifin, Israel. 4. Sagol Center for Hyperbaric Medicine and Research, Shamir Medical Center, Zerifin, Israel.
Abstract
OBJECTIVES: To compare the visual outcome of patients treated for non-arthritic central retinal artery occlusion (CRAO) in a medical centre that uses hyperbaric oxygen therapy (HBOT) as part of the standard of care (SOC) to medical centres that does not. METHODS: The study included data from two tertiary medical centres. The medical records of all patients diagnosed with non-arthritic CRAO without a patent cilioretinal artery between January 2010 and December 2018 in two tertiary medical centres were reviewed. RESULTS: One hundred and twenty-one patients were treated by HBOT and 23 patients received only SOC. In the HBOT group, best-corrected visual acuity (BCVA) improved from 2.89 ± 0.98 logMAR at presentation to 2.15 ± 1.07 logMAR upon the end of HBOT (P < 0.001), while the SOC group had no significant improvement, from 3.04 ± 0.82 logMAR at presentation to 2.80 ± 1.50 logMAR (P = 0.24). With adjustment for age, gender, and the duration of symptoms, final BCVA in the HBOT group was significantly better compared to the control group (P = 0.023). Rates of patients achieving vision of 20/200 or better were similar between groups (17.4% vs. 19.8%, P = 0.523). CONCLUSION: Utilizing HBOT as part of the SOC for CRAO improves the final visual outcome. HBOT is safe and can be implemented, if available, as part of SOC in all tertiary medical centres.
OBJECTIVES: To compare the visual outcome of patients treated for non-arthritic central retinal artery occlusion (CRAO) in a medical centre that uses hyperbaric oxygen therapy (HBOT) as part of the standard of care (SOC) to medical centres that does not. METHODS: The study included data from two tertiary medical centres. The medical records of all patients diagnosed with non-arthritic CRAO without a patent cilioretinal artery between January 2010 and December 2018 in two tertiary medical centres were reviewed. RESULTS: One hundred and twenty-one patients were treated by HBOT and 23 patients received only SOC. In the HBOT group, best-corrected visual acuity (BCVA) improved from 2.89 ± 0.98 logMAR at presentation to 2.15 ± 1.07 logMAR upon the end of HBOT (P < 0.001), while the SOC group had no significant improvement, from 3.04 ± 0.82 logMAR at presentation to 2.80 ± 1.50 logMAR (P = 0.24). With adjustment for age, gender, and the duration of symptoms, final BCVA in the HBOT group was significantly better compared to the control group (P = 0.023). Rates of patients achieving vision of 20/200 or better were similar between groups (17.4% vs. 19.8%, P = 0.523). CONCLUSION: Utilizing HBOT as part of the SOC for CRAO improves the final visual outcome. HBOT is safe and can be implemented, if available, as part of SOC in all tertiary medical centres.
Authors: Andreas W A Weinberger; Ullrich P F Siekmann; Sebastian Wolf; Rolf Rossaint; Bernd Kirchhof; Norbert F Schrage Journal: Klin Monbl Augenheilkd Date: 2002-10 Impact factor: 0.700
Authors: Luca Rosignoli; Edward R Chu; John E Carter; Daniel A Johnson; Jeong-Hyeon Sohn; Sepehr Bahadorani Journal: Korean J Ophthalmol Date: 2021-11-08