Literature DB >> 34137373

Where ketamine and dopamine collide.

David J Marcus1, Michael R Bruchas2.   

Abstract

Ketamine strengthens connections between two brain regions that are involved in the production and regulation of dopamine, which may explain how the drug can alleviate depression.
© 2021, Marcus and Bruchas.

Entities:  

Keywords:  VTA; antidepressants; aversive learning; dopamine; ketamine; mPFC; mouse; neuroscience

Year:  2021        PMID： 34137373     DOI： 10.7554/eLife.70148

Source DB:  PubMed          Journal:  Elife        ISSN： 2050-084X            Impact factor:   8.140


  2 in total

Review 1.  Key considerations for the use of ketamine and esketamine for the treatment of depression: focusing on administration, safety, and tolerability.

Authors:  Michael D Kritzer; Chi-Un Pae; Prakash S Masand
Journal:  Expert Opin Drug Saf       Date:  2022-04-29       Impact factor: 4.011

Review 2.  Uncovering the Underlying Mechanisms of Ketamine as a Novel Antidepressant.

Authors:  Songbai Xu; Xiaoxiao Yao; Bingjin Li; Ranji Cui; Cuilin Zhu; Yao Wang; Wei Yang
Journal:  Front Pharmacol       Date:  2022-07-07       Impact factor: 5.988
  2 in total

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