Literature DB >> 34137079

Prioritizing heart transplantation during the COVID-19 pandemic.

Keki R Balsara1, Zakiur Rahaman1, Emily Sandhaus2, Jordan Hoffman1, Sandip Zalawadiya2, William McMaster1, Joann Lindenfeld2, Mark Wigger2, Tarek Absi1, Douglas M Brinkley2, Jonathan Menachem2, Lynn Punnoose2, Suzie Sacks2, Kelly Schlendorf2, Ashish S Shah1.   

Abstract

BACKGROUND: Coronavirus disease 2019 (COVID-19) has significantly impacted the healthcare landscape in the United States in a variety of ways including a nation-wide reduction in operative volume. The impact of COVID-19 on the availability of donor organs and the impact on solid organ transplant remains unclear. We examine the impact of COVID-19 on a single, large-volume heart transplant program.
METHODS: A retrospective chart review was performed examining all adult heart transplants performed at a single institution between March 2020 and June 2020. This was compared to the same time frame in 2019. We examined incidence of primary graft dysfunction, continuous renal replacement therapy (CRRT) and 30-day survival.
RESULTS: From March to June 2020, 43 orthotopic heart transplants were performed compared to 31 performed during 2019. Donor and recipient demographics demonstrated no differences. There was no difference in 30-day survival. There was a statistically significant difference in incidence of postoperative CRRT (9/31 vs. 3/43; p = .01). There was a statistically significant difference in race (23 W/8B/1AA vs. 30 W/13B; p = .029).
CONCLUSION: We demonstrate that a single, large-volume transplant program was able to grow volume with little difference in donor variables and clinical outcomes following transplant. While multiple reasons are possible, most likely the reduction of volume at other programs allowed us to utilize organs to which we would not have previously had access. More significantly, our growth in volume was coupled with no instances of COVID-19 infection or transmission amongst patients or staff due to an aggressive testing and surveillance program.
© 2021 Wiley Periodicals LLC.

Entities:  

Keywords:  COVID-19; heart transplantation; resource allocation

Year:  2021        PMID: 34137079     DOI: 10.1111/jocs.15731

Source DB:  PubMed          Journal:  J Card Surg        ISSN: 0886-0440            Impact factor:   1.620


  2 in total

1.  Heart transplantations amidst the COVID-19 pandemic: "In the midst of chaos, there is also opportunity".

Authors:  Andrea Amabile; Arnar Geirsson
Journal:  J Card Surg       Date:  2021-06-08       Impact factor: 1.778

Review 2.  Development of an organ procurement team in South Australia in response to COVID-19.

Authors:  Damian Joseph Gimpel; Gareth Crouch; Malgorzata Szpytma; Annette Mazzone; Robert A Baker; Jayme S Bennetts
Journal:  ANZ J Surg       Date:  2022-05-23       Impact factor: 2.025

  2 in total

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