Literature DB >> 34134878

Personal, provider and system level barriers and enablers for hepatitis C treatment in the era of direct-acting antivirals: Experiences of patients who inject drugs accessing treatment in general practice settings in Australia.

Emma Heard1, Andrew Smirnov2, Luciana Massi3, Linda A Selvey4.   

Abstract

Direct acting antiviral (DAA) treatment has made the elimination of hepatitis C virus (HCV) a realisable global public health goal and people who inject drugs are a key target population. This study investigates barriers and enablers to DAA treatment of HCV in general practice settings in Australia, from the patient perspective. Semi-structured interviews were conducted with 28 patients; of these patients, seventeen participants were currently on opioid agonist therapy, and four were currently injecting drugs. Thematic data analysis was undertaken and a personal, provider and systems framework was used to describe the barriers and enablers to DAA treatment. Results suggest a range of initiatives are required to support the uptake of DAA in general practice settings. These include the provision of formalised peer information and support, and increasing the accessibility of blood tests and liver assessment on-site. Further, there remains a need to address stigma and discrimination affecting people who inject drugs in community healthcare settings.
Copyright © 2021 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  DAA; Direct-acting antivirals; General practice; Hepatitis C treatment; Hepatitis C virus; Peer support

Mesh:

Substances:

Year:  2021        PMID: 34134878     DOI: 10.1016/j.jsat.2021.108460

Source DB:  PubMed          Journal:  J Subst Abuse Treat        ISSN: 0740-5472


  3 in total

1.  Hepatitis C cure as a 'gathering': Attending to the social and material relations of hepatitis C treatment.

Authors:  Adrian Farrugia; Renae Fomiatti; Suzanne Fraser; David Moore; Michael Edwards; Elizabeth Birbilis; Carla Treloar
Journal:  Sociol Health Illn       Date:  2022-04-01

2.  Retreatment for hepatitis C virus direct acting antiviral therapy virological failure in primary and tertiary settings: the REACH-C cohort.

Authors:  Joanne M Carson; Behzad Hajarizadeh; Josh Hanson; James O'Beirne; David Iser; Phillip Read; Anne Balcomb; Jane Davies; Joseph S Doyle; Jasmine Yee; Marianne Martinello; Philippa Marks; Gail V Matthews; Gregory J Dore
Journal:  J Viral Hepat       Date:  2022-05-18       Impact factor: 3.517

3.  Changes in Health-related Quality of Life for Hepatitis C Virus-Infected People Who Inject Drugs While on Opioid Agonist Treatment Following Sustained Virologic Response.

Authors:  Mirinda Ann Gormley; Matthew J Akiyama; Lior Rennert; Kerry A Howard; Brianna L Norton; Irene Pericot-Valverde; Sam Muench; Moonseong Heo; Alain H Litwin
Journal:  Clin Infect Dis       Date:  2022-05-03       Impact factor: 20.999

  3 in total

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