Literature DB >> 34133014

C1-2 rotatory subluxation as a presenting sign in juvenile rheumatoid arthritis.

A T Whitaker1, M P Glotzbecker2.   

Abstract

STUDY
DESIGN: Case report.
INTRODUCTION: Juvenile rheumatoid arthritis (JRA) typically presents with fever, rash, anterior uveitis, and/or joint pain. We present three cases with initial torticollis due to rotatory subluxation of C1-C2 as an initial sign of JRA. CASE REPORTS: Three girls, ages 5-9, presented with C1-2 rotatory subluxation. Traction was able to reduce the atlanto-axial joint in all cases. Based on imaging, history, exam, and laboratory results, they were diagnosed with JRA. After reduction of the atlantoaxial joint, they were transitioned to a halo vest and disease-modifying antirheumatic drugs (DMARDs). The older 2 children underwent C1-2 fusion. The younger child has minimal symptoms and has not undergone surgical intervention 4 years from initial presentation.
CONCLUSION: Rotatory subluxation can be the first presenting sign of JRA. Younger children may be able to be treated conservatively with traction and medication, while older children may require occiput to C2 fusion due to bony destruction and basilar invagination. LEVEL OF EVIDENCE: IV.

Entities:  

Keywords:  Juvenile rheumatoid arthritis; Pediatric atlantoaxial subluxation

Year:  2021        PMID: 34133014     DOI: 10.1007/s43390-021-00372-w

Source DB:  PubMed          Journal:  Spine Deform        ISSN: 2212-134X


  7 in total

1.  Radiological cervical spine involvement in young adults with polyarticular juvenile idiopathic arthritis.

Authors:  Muriel Elhai; Julien Wipff; Ramin Bazeli; Véronique Freire; Antoine Feydy; Jean-Luc Drapé; Pierre Quartier; André Kahan; Chantal Job-Deslandre
Journal:  Rheumatology (Oxford)       Date:  2012-04-17       Impact factor: 7.580

2.  Successful treatment with methotrexate of a child with atlantoaxial subluxation from enthesitis-related arthritis.

Authors:  N Kobayashi; K Yasui; H Nagumo; K Agenatsu; K Koike
Journal:  Clin Exp Rheumatol       Date:  2006 Mar-Apr       Impact factor: 4.473

3.  Subaxial cervical vertebrae in patients with juvenile idiopathic arthritis--something special?

Authors:  Kira Endén; Kari Laiho; Hannu Kautiainen; Marja Arkela-Kautiainen; Eero Belt; Markku Kauppi
Journal:  Joint Bone Spine       Date:  2009-02-11       Impact factor: 4.929

4.  Atlanto-axial subluxation in a patient with polyarticular juvenile idiopathic arthritis: clinical and radiological response to infliximab.

Authors:  Z Cannioto; A Taddio; L Lepore; F Zennaro
Journal:  Clin Exp Rheumatol       Date:  2008 Jul-Aug       Impact factor: 4.473

5.  Atlanto-axial joint involvement as exclusive manifestation of juvenile idiopathic arthritis (JIA).

Authors:  A Taddio; M C Pellegrin; M Gregori; S Wientroub; S Padeh; L Lepore
Journal:  Clin Exp Rheumatol       Date:  2011-09-01       Impact factor: 4.473

6.  Rotatory subluxation: experience from the Hospital for Sick Children.

Authors:  Alexandra D Beier; Shobhan Vachhrajani; Simon H Bayerl; Claudia Y Diaz Aguilar; Maria Lamberti-Pasculli; James M Drake
Journal:  J Neurosurg Pediatr       Date:  2012-02       Impact factor: 2.375

7.  Atlantoaxial subluxation as an early manifestation in an adolescent with undifferentiated spondyloarthritis: a case report and review of the literature.

Authors:  Eyal Muscal; Krishna B Satyan; Andrew Jea
Journal:  J Med Case Rep       Date:  2011-07-03
  7 in total

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