Degradation of amoxicillin with sono, photo, and sonophotocatalytic oxidation under low-frequency ultrasound and visible light.

The presence of pharmaceutically active compounds in aquatic bodies is a global concern, and suitable treatment technologies are required. In this study, the efficacy of photocatalytic, sonocatalytic, and sonophotocatalytic oxidation processes for the degradation of amoxicillin (AMX) was investigated using visible light with N doped TiO2 (N-TiO2) nanoparticles as the catalyst and low-frequency ultrasound in a novel multifrequency reactor. The influence of different operational parameters on the extent of AMX degradation was studied. Sonophotocatalytic oxidation was found more efficient for AMX degradation when compared to photocatalysis or sonocatalysis alone, and may be due to the reduced bandgap of the catalyst, enhanced cavitation effect due to the presence of the solid catalyst, and improved mass transfer of pollutants. AMX degradation during sono, photo, and sonophotocatalytic oxidation processes was in good agreement with pseudo-first-order kinetics. Empirical kinetic models were also developed using multiple linear regression for predicting the degradation efficiency accounting for the operational parameters. Scavenger experiments suggested that •OH radicals largely contributed to AMX degradation, and a plausible mechanism for degradation was proposed. Further, possible degradation pathways for all three treatment processes are also proposed after identifying the degradation products.