Effective elastic modulus of an intact cornea related to indentation behavior: A comparison between the Hertz model and Johnson-Kendall-Roberts model.

In this study, a macro-indentation test on the submillimeter scale was performed to analyze the indentation behavior of an intact cornea under physiological pressures. The Hertz and Johnson-Kendall-Roberts (JKR) models were employed to solve the elastic modulus (E) of the intact cornea. The relevant detailed analysis showed that the JKR model, which accounted for the contribution from the adhesion energy, could be used to obtain the E values that were more than two-folds of those obtained from the Hertz model, which only considered the external force. Compared with the uniaxial tension test in vitro, unlike the elastic Hertz-model, the E values under physiological pressures that were obtained with the JKR model were between the lower and upper limits of corneal material. This phenomenon indicated that the JKR model could be used to obtain reasonably effective E values of an intact cornea under physiological pressures.